Abstract
Retrospective study was carried out in 1,15,851 consecutive births in five hospitals, and prospective study of 10,415 consecutive births in one hospital of West Bengal. The overall frequency of congenital defects was 4.42/1000 live births. Incidence of NTD and talipes was predominant in rainy season, whereas cleft palate with/without hare lip had highest frequency during winter. Incidence of these anomalies decreased with increasing birth order. The frequency was noted to decline with increasing maternal age, 21–25 years age group had maximum number of malformed babies. Sex ratio and religion, however, did not have any correlation with the incidence of these malformations. When comparison was done between urban and rural population no statistically significant variation was observed.
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References
Czeizel A, Kis-Varga A. Mutation surveillance of sentinel anomalies in Hungary 1980-1984.Mut Res 1987; 186: 73–79.
Mulvihill JJ, Czeizel A. A 1983 view of sentinel phenotypes.Mut Res 1983; 123: 345–361.
Roy Choudhury A, Taluker G, Sharma A. Neonatal congenital malformations in Calcutta.Indian Pediatr 1984; 21: 399–405.
Bannerjee AR, Basu M. Preliminary study on congenital malformations in Calcutta.Bull Univ College of Medicine Calcutta, 1973; 9–10.
Ghosh AK, Chatterjee S, Piplai C. Congenital malformation in the Bengali newborn babies.Coll Anthropol 1979; 3: 255–260.
Guha A, Mukherjee DP. Trends of congenital malformations in neonates in two Calcutta hospitals with special reference of anencephaly.J Indian Anthrop Soc 1980; 15: 157–166.
Roy Choudhury A, Mukherjee M, Talukder G, Sharma A. Incidence of major congenital malformations in urbanised areas of West Bengal. 1989a (Communicated).
Roy Choudhury A, Mukherjee M, Talukder G, Sharma A. Incidence of congenital malformations in relation to sea sonal variation.Indian Pediatr 1988; 25: 1218–1221.
Master-Notani P, Kolah P, Sanghvi LD. Congenital malformation in the newborn in Bombay.Acta Genet Basel 1968;: 18 : 97–108,193-205.
Stevenson AC, Johnston HA, Golding DR, Stewart MIP. Congenital malformations : A report of a study of series of consecutive births in 24 centres.Bull WHO 1966; Suppl. to Vol 34.
Garg VK, Singh MN, Mishra OP, Gupta R, Bhatia BP, Bhargava V. Neonatal mortality rate: a hospital study.Indian Pediatr 1987; 24:639–644.
Goravalingappa JP, Nashi HK. Congenital malformations in a study of 2398 consecutive births.Indian J Med Res 1979; 69: 140–146.
Kalra A, Kalra K, Sharma V, Singh M, Dayal RS. Congenital malformations.Indian Pediatr 1984; 21: 945–950.
Khurana O, Warey P, Dave AB, Saikhedkar R. Perinatal mortality trends in steel plant hospitals.Indian Pediatr 1987; 24:633–638.
Verma IC, Mathews AR. Congenital malformations in India. In :People of India, XV International Congress of Genetics, New Delhi, 1983; 70–84.
Chimara RK, Singh S. East West differentials in congenital malformations.Indian J Pediatr 1982; 49: 325–330.
Talukder G. Neural tube defects in Calcutta area.J Ass Phys India 1985; 33: 402–403.
Talukder G. Genetical causes of foetal loss and congenital malformations in man. In :Perspectives in Cytology and Genetics eds. G.K. Manna and U. Sinha 1986; 5 : 21–26.
Ghosh S. Infant and childhood mortality: editorial.Indian Pediatr 1987; 24 : 613–618.
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Choudhury, A.R., Mukherjee, M., Sharma, A. et al. Study of 1,26,266 consecutive births for major congenital defects. Indian J Pediatr 56, 493–499 (1989). https://doi.org/10.1007/BF02722422
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DOI: https://doi.org/10.1007/BF02722422