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Post-streptococcal acute glomerulonephritis : A clinical, bacteriological and serological study

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Abstract

Eight hundred and sixty four children were admitted with Acute poststreptococcal glomerulonephritis (APSGN) at the Institute for Child Health, Madras, during the period January 1981 to January 1983. Majority of the cases followed infected scabies or impetigo. 135 children were investigated and followed up for a period of 1–2 years. The disease had an excellent prognosis in these children. None of those examined 2 years after discharge had proteinuria or hypertension. Group A beta hemolytic streptococcus (BHS) was isolated in 13.4% of patients and 11.25% of skin infection controls. Eight different T types were identified in patients and 6 T types in pyoderma cases. All patients and 87% of skin infection controls had elevated anti-D Nase B titres, while ASO titres were not significantly raised.

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References

  1. Svartman M, Potter EV, Findlea JF ct al. Epidemic scabies and acute glomerulonephritis.Lancet 1972; i: 249–251.

    Article  Google Scholar 

  2. Dillon HC, Reeves Mary S, Maxted WR. Acute glomerulonephritis following skin infection due to streptococcus M type 2.Lancet 1968; i: 543–545.

    Article  Google Scholar 

  3. Reinstein CR. Epidemic Nephritis at Red Lake, Minnesota.Pediatr 1955; 25: 47–49.

    Google Scholar 

  4. Koshi G, Webb JKG, Meyers RM. Association of preceding streptococcal skin infection and acute glomerulonephritis in children in South India.Indian J Med Res 1968; 56: 951–964.

    PubMed  CAS  Google Scholar 

  5. Koshi G. Serological types of streptococci encountered in Southern India.Indian J Med Res 1976; 3: 64–68.

    Google Scholar 

  6. Moddy MD, Padula J, Lizana D, Hall CT. Epidemiologic characterisation of Group A streptococci by T agglutination and M precipitation tests in the public health laboratory.Health Lab 1965; 2: 149–151.

    Google Scholar 

  7. Nelson J, Ayoubn EM, Wannamaker LW. Streptococcal anti desoxyribonuclease B microtechnique determination.J Lab Clin Med 1968; 71: 867–869.

    PubMed  CAS  Google Scholar 

  8. Koshi G. Anti streptolyslin test by microtechnique method.Indian J Med Res 1971; 59: 9–10.

    Google Scholar 

  9. Dillon HC Jr. Streptococcal skin infection and acute glomerulonephritis.Post grad MedJ 1970; 46: 641–652.

    Article  Google Scholar 

  10. Manhas RS, Patwari A, Raina C, Singh A. Acute Nephritis in Kashmiri children. Clinical and Epidemiological profile (a study of 350 cases)Indian Pediatr 1979; 16: 1015–1017.

    PubMed  CAS  Google Scholar 

  11. Hayes John S. Observations on Post-streptococcal glomerulonephritis as seen at the Port-Of-Spain General Hospital. In: Stanley Read and John Zabriskie (Eds)Streptococcal diseases and the immune response". London, Academic Press, 1980: 581–583.

    Google Scholar 

  12. Dodge W, Spargo B, Travis L et al. Poststreptoccal glomerulonephritis a prospective study in children.New Engl J Med 1972; 286: 273–276.

    Article  PubMed  CAS  Google Scholar 

  13. Potter EV, O’Keefe TJ, Svartman M et al. Relationship of SerumB l C globulin to fibrinolysis in patients with Post-streptococcal acute glomerulonephritis.J Lab Clin Med 1973; 82: 776–778.

    PubMed  CAS  Google Scholar 

  14. Koshi G. Serological types of streptococci encountered in Southern India.Indian J Med Res1976;64 3–8.

    Google Scholar 

  15. Prakash K, Ravindran PC, Sharma KB. T sero types of Group A streptococci in various clinical conditions and school children in North India.Indian J Med Res 1977; 65: 782–785.

    PubMed  CAS  Google Scholar 

  16. Jerath VP, Singh R, Kumari S. Haemolytic streptococcus Group A in the skin and throat of patients of scabies with Nephritis.Indian J Med Res 1979; 69: 933–936.

    PubMed  CAS  Google Scholar 

  17. Svartman M, Potter EV, King TP, Earle D. Streptococcal infection of scabitic lesions related to acute glomerulonephritis in Trinidad.J Lab Clin Med 1973; 81: 182–185.

    PubMed  CAS  Google Scholar 

  18. Dillon HC, Reeves MC. Streptococcal immune response in Nephritis after skin infection.Am J Med 1974; 56: 3–5.

    Article  Google Scholar 

  19. Wannamaker LW. Difference between streptococcal infection of throat and skin.New Eng J Med 1970; 282: 23–31.

    Article  PubMed  CAS  Google Scholar 

  20. Kaplan EL, Anthony BF, Wannamaker LW. Influence of site of infection on immune response to Group A streptococci.J Clin Immunol 1970; 19: 1405–1410.

    Google Scholar 

  21. Bisco A. Factors influencing serum antibody responses in streptococcal Pyoderma.J Lab Clin Med 1973; 81: 410–412.

    Google Scholar 

  22. Jerath VP, Singh R, Kumari S. Haemolytic streptococci Group A in the skin and throat of patients of scabies with Nephritis.Indian J Med Res 1979; 69: 933–938.

    PubMed  CAS  Google Scholar 

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  1. Department of Immunology, Tuberculosis Research Centre, Madras

    Sarala Rajajee

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  1. Sarala Rajajee
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Rajajee, S. Post-streptococcal acute glomerulonephritis : A clinical, bacteriological and serological study. Indian J Pediatr 57, 775–780 (1990). https://doi.org/10.1007/BF02722275

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