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Study of anti tetanus IgG and IgM levels in maternal and cord sera by enzyme linked immunosorbent assay (ELISA)

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Abstract

The study was done to determine IgG and IgM antitetanus antibodies in mothers after antenatal immunization, and extent of transfer to the baby as measured by cord levels of tetanus specific IgG and IgM by ELISA using enzyme penicillinase and to study the effect of nutritional status of mothers on antibody response to tetanus toxoid and corresponding cord levels also to determine the number of doses required for protective antibody levels in cord blood. The results obtained in sera of 100 mothers at the time of delivery and their respective cord sera and results of 43 different control sera are discussed using ELISA technique.

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Authors and Affiliations

  1. Microbiology Section, Aditya Pediatric Research Laboratory, Bai Jerbai Wadia Hospital for Children, 400 012, Parel, Bombay

    Satish Sundar, Neelam Wagle, B. L. Varudkar, Avinash Vaidya &  S. M. Merchant

Authors
  1. Satish Sundar
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  2. Neelam Wagle
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  3. B. L. Varudkar
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  4. Avinash Vaidya
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  5. S. M. Merchant
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Sundar, S., Wagle, N., Varudkar, B.L. et al. Study of anti tetanus IgG and IgM levels in maternal and cord sera by enzyme linked immunosorbent assay (ELISA). Indian J Pediatr 57, 763–770 (1990). https://doi.org/10.1007/BF02722271

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  • DOI: https://doi.org/10.1007/BF02722271

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