Zusammenfassung
Trotz adäquater Antibiotikatherapie beträgt die Zahl der letalen generalisierten Infektionen bei transplantierten Patienten je nach Erregerspektrum bis über 70%. Wir berichten von einer Patientin mit fulminanter Pseudomonaspneumonie und-sepsis nach orthotoper Lebertransplantation (OLT), bei der durch eine adjuvante Therapie mit IgM-angereicherter Immunglobulinlösung sowie fibronektinangereichertem Serum zusätzlich zur antibiotischen Therapie die Sepsis beherrscht werden konnte.
Summary
We report about a female patient after orthotopic liver transplantation suffering from pneumonia and sepsis caused by pseudomonas aeruginosa. Additionally to antibiotic therapy, our patient was treated with IgM-enriched immunoglobulin solution and fibronectin-enriched serum. Although the patient;s general condition was poor, sepsis and pneumonia were treated successfully while immunosuppressive therapy was modified, but not discontinued. We conclude that additional therapy with IgM-enriched immunoglobulin solution and fibronectin-enriched serum can contribute to the treatment of severe infections in immunosuppressed patients.
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Sautner, T., Graninger, W., Gnant, M. et al. Adjuvante Therapie einer Pseudomonas-pneumonie und-sepsis nach orthotoper Leber-transplantation mit einer IgM-angereicherten Immunglobulinlösung und fibronektin-angereichertem Serum. Acta Chir Austriaca 21, 304–305 (1989). https://doi.org/10.1007/BF02721391
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DOI: https://doi.org/10.1007/BF02721391
Schlüsselwörter
- Lebertransplantation
- Immunsuppression
- Pseudomonasinfektion
- IgM
- angereicherte Immunglobulinlösung
- fibronektinangereichertes Serum