Abstract
We attempted to detect early signs of asbestos-induced lung disease in groups of workers in a factory which manufactured heat-resistant and friction composites. Chest auscultation results, scored on the frequency, persistence, and distribution of rales, were 2+ in 25/79 asbestos-exposed workers (32%) vs. 1/22 non-exposed workers (5%). Vital capacity was slightly but significantly reduced in two of three subgroups of asbestos workers compared to non-exposed workers. Although none of the workers had asbestosis according to clinical criteria, and only 2 had more than slight parenchymal lesions on a 70 mm chest x-ray film, the asbestos-exposed men as a group had signs of early parenchymal lung disease which were absent or minimal in the control subjects. If medical examinations of asbestos workers are to be useful in detecting early lung disease in individuals or are to serve as a "biological monitor" of the work environment, they should at least include chest auscultation, as well as lung function tests which are adequately standardized to allow definition of slight degrees of lung function loss.
Similar content being viewed by others
References
Becklake, M.R.: Asbestos-related diseases of the lung and other organs: Their epidemiology and implications for clinical practice. Amer. Rev. Respir. Dis.114, 187–227 (1976)
Bohlig, H., Bristol, L.J., Cartier, P.H., et al.: UICC/Cincinnati classification of the radiographic appearances of pneumoconioses: a cooperative study by the UICC committee. Chest58, 57–67 (1970)
Damon, A.: Negro-white differences in pulmonary function (vital capacity, timed vital capacity, and expiratory flow rate). Human Biol.38, 380–393 (1966)
Edwards, G.H., Lynch, J.R.: The method used by the U.S. Public Health Service for enumeration of asbestos dust on membrane filters. Ann. Occup. Hyg.11, 1–6 (1968)
Ferris, B.G., Jr., Anderson, D.O., Zickmantel, R.: Prediction values for screening tests of pulmonary function. Amer. Rev. Respir. Dis.91, 252–261 (1965)
Hall, G.J.L., Gandevia, B.: Relationship of the loose cough sign to daily sputum volume; observer variation in its detection. Brit. J. Prev. Soc. Med.25, 109–113 (1971)
Jodoin, G., Gibbs, G.W., Macklem, P.T., McDonald, J.C., Becklake, M.R.: Early effects of asbestos exposure on lung function. Amer. Rev. Respir. Dis.104, 525–535 (1971)
Leathart, G.L.: Pulmonary function tests in asbestos workers. Trans. Soc. Occup. Med.18, 49–55 (1968)
Medical Research Council’s Committee on the Aetiology of Chronic Bronchitis: Standardized questionnaires on respiratory symptoms. Brit. Med. J.2, 1665 (1960)
Murphy, R.L.H., Ferris, B.G., Jr., Burgess, W.A., Worcester, J., Gaensler, E.A.: Effects of low concentrations of asbestos: Clinical, environmental, radiologic and epidemiologic observations in shipyard pipe coverers and controls. N. Engl. J. Med.285, 1271–1278 (1971)
Murphy, R.L.H., Jr., Sorensen, K.: Chest auscultation in the diagnosis of pulmonary asbestosis. J. Occup. Med.15, 272–276 (1973)
Schoenberg, J.B., Mitchell, C.A.: Implementation of the federal Asbestos Standard in Connecticut. J. Occup. Med.16, 781–784 (1974)
Snedecor, G.W., Cochran, W.G.: Statistical Methods, ed. 6. Ames, Iowa: The Iowa State University Press, 1967
Standard for exposure to asbestos dust. Federal Register37, 11318–11322 (1972)
Virgulto, J., Bouhuys, A.: Electronic circuits for recording of maximum expiratory flow-volume (MEFV) curves. J. Appl. Physiol.35, 145–147 (1973)
Weiss, W.: Cigarette smoking, asbestos, and pulmonary fibrosis. Amer. Rev. Respir. Dis.104, 223–227 (1971)
Author information
Authors and Affiliations
Additional information
Supported in part by U.S.P.H.S. Grant HL-14179 from the National Heart, Lung and Blood Institute, National Institutes of Health.
Rights and permissions
About this article
Cite this article
Mitchell, C.A., Charney, M. & Schoenberg, J.B. Early lung disease in asbestos-product workers. Lung 154, 261–272 (1976). https://doi.org/10.1007/BF02713542
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02713542