Skip to main content
Log in

Early lung disease in asbestos-product workers

  • Published:
Lung Aims and scope Submit manuscript

Abstract

We attempted to detect early signs of asbestos-induced lung disease in groups of workers in a factory which manufactured heat-resistant and friction composites. Chest auscultation results, scored on the frequency, persistence, and distribution of rales, were 2+ in 25/79 asbestos-exposed workers (32%) vs. 1/22 non-exposed workers (5%). Vital capacity was slightly but significantly reduced in two of three subgroups of asbestos workers compared to non-exposed workers. Although none of the workers had asbestosis according to clinical criteria, and only 2 had more than slight parenchymal lesions on a 70 mm chest x-ray film, the asbestos-exposed men as a group had signs of early parenchymal lung disease which were absent or minimal in the control subjects. If medical examinations of asbestos workers are to be useful in detecting early lung disease in individuals or are to serve as a "biological monitor" of the work environment, they should at least include chest auscultation, as well as lung function tests which are adequately standardized to allow definition of slight degrees of lung function loss.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Becklake, M.R.: Asbestos-related diseases of the lung and other organs: Their epidemiology and implications for clinical practice. Amer. Rev. Respir. Dis.114, 187–227 (1976)

    CAS  Google Scholar 

  2. Bohlig, H., Bristol, L.J., Cartier, P.H., et al.: UICC/Cincinnati classification of the radiographic appearances of pneumoconioses: a cooperative study by the UICC committee. Chest58, 57–67 (1970)

    Google Scholar 

  3. Damon, A.: Negro-white differences in pulmonary function (vital capacity, timed vital capacity, and expiratory flow rate). Human Biol.38, 380–393 (1966)

    Google Scholar 

  4. Edwards, G.H., Lynch, J.R.: The method used by the U.S. Public Health Service for enumeration of asbestos dust on membrane filters. Ann. Occup. Hyg.11, 1–6 (1968)

    PubMed  CAS  Google Scholar 

  5. Ferris, B.G., Jr., Anderson, D.O., Zickmantel, R.: Prediction values for screening tests of pulmonary function. Amer. Rev. Respir. Dis.91, 252–261 (1965)

    Google Scholar 

  6. Hall, G.J.L., Gandevia, B.: Relationship of the loose cough sign to daily sputum volume; observer variation in its detection. Brit. J. Prev. Soc. Med.25, 109–113 (1971)

    CAS  Google Scholar 

  7. Jodoin, G., Gibbs, G.W., Macklem, P.T., McDonald, J.C., Becklake, M.R.: Early effects of asbestos exposure on lung function. Amer. Rev. Respir. Dis.104, 525–535 (1971)

    CAS  Google Scholar 

  8. Leathart, G.L.: Pulmonary function tests in asbestos workers. Trans. Soc. Occup. Med.18, 49–55 (1968)

    Article  PubMed  CAS  Google Scholar 

  9. Medical Research Council’s Committee on the Aetiology of Chronic Bronchitis: Standardized questionnaires on respiratory symptoms. Brit. Med. J.2, 1665 (1960)

    Google Scholar 

  10. Murphy, R.L.H., Ferris, B.G., Jr., Burgess, W.A., Worcester, J., Gaensler, E.A.: Effects of low concentrations of asbestos: Clinical, environmental, radiologic and epidemiologic observations in shipyard pipe coverers and controls. N. Engl. J. Med.285, 1271–1278 (1971)

    Article  PubMed  CAS  Google Scholar 

  11. Murphy, R.L.H., Jr., Sorensen, K.: Chest auscultation in the diagnosis of pulmonary asbestosis. J. Occup. Med.15, 272–276 (1973)

    PubMed  Google Scholar 

  12. Schoenberg, J.B., Mitchell, C.A.: Implementation of the federal Asbestos Standard in Connecticut. J. Occup. Med.16, 781–784 (1974)

    Article  PubMed  CAS  Google Scholar 

  13. Snedecor, G.W., Cochran, W.G.: Statistical Methods, ed. 6. Ames, Iowa: The Iowa State University Press, 1967

    Google Scholar 

  14. Standard for exposure to asbestos dust. Federal Register37, 11318–11322 (1972)

  15. Virgulto, J., Bouhuys, A.: Electronic circuits for recording of maximum expiratory flow-volume (MEFV) curves. J. Appl. Physiol.35, 145–147 (1973)

    PubMed  CAS  Google Scholar 

  16. Weiss, W.: Cigarette smoking, asbestos, and pulmonary fibrosis. Amer. Rev. Respir. Dis.104, 223–227 (1971)

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Supported in part by U.S.P.H.S. Grant HL-14179 from the National Heart, Lung and Blood Institute, National Institutes of Health.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mitchell, C.A., Charney, M. & Schoenberg, J.B. Early lung disease in asbestos-product workers. Lung 154, 261–272 (1976). https://doi.org/10.1007/BF02713542

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02713542

Key words

Navigation