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Sustained remission of teratoma with malignant transformation to rhabdomyosarcoma treated with surgery and tailored chemotherapy

Remisión prolongada de un teratoma con transformación maligna a rabdomiosarcoma tratado con cirugía y quimioterapia adaptada

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Resumen

El síndrome del teratoma con transformación maligna hacia un tumor de células no germinales es una situación infrecuente y se sabe poco acerca de su manejo óptimo. Presentamos el caso de un rabdomiosarcoma transformado a partir de un teratoma retroperitoneal en un paciente de 19 años. El paciente había sido tratado 9 meses antes por un carcinoma embrionario testicular y posteriormente se presentó con una masa heterogénea retroperitoneal de 16 cm y marcadores tumorales normales. Con el diagnóstico de sospecha de síndrome del teratoma maduro(growing teratoma) fue sometido a una linfadenectomía retroperitoneal y exéresis completa de la masa. El examen histológico de la pieza reveló la presencia de un teratoma con transformación maligna a rabdomiosarcoma. El paciente racibió quimioterapia adyuvante adaptada al componente sarcomatoso estando en la actualidad sin evidencia de recaída tras 20 meses de la cirugía.

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Authors and Affiliations

  1. Servicio de Oncología Médica, Hospital de Gran Canaria Dr. Negrín, Barranco de la Ballena s/n, 35020, Las Palmas de Gran Canaria, Spain

    David Aguiar Bujanda, José Aguiar Morales & Uriel Bohn Sarmiento

  2. Servicio de Urología, Hospital de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Spain

    Francisco Deniz Guerra

  3. Servicio de Anatomía Patológica, Hospital de Gran Canaria Dr. Negrín. Las Palmas de Gran Canaria, Spain

    Rey dela Rosa

Authors
  1. David Aguiar Bujanda
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  2. Francisco Deniz Guerra
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  3. Rey dela Rosa
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  4. José Aguiar Morales
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  5. Uriel Bohn Sarmiento
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Correspondence to David Aguiar Bujanda.

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Bujanda, D.A., Guerra, F.D., dela Rosa, R. et al. Sustained remission of teratoma with malignant transformation to rhabdomyosarcoma treated with surgery and tailored chemotherapy. Rev Oncol 6, 491–492 (2004). https://doi.org/10.1007/BF02713087

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  • DOI: https://doi.org/10.1007/BF02713087

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