Skip to main content
Log in

Postoperative radiotherapy with simultaneous chemotherapy in high-risk squamous cell carcinoma of the head and neck: a novel standard that opens new questions

  • Editorial
  • Published:
Clinical and Translational Oncology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Felman M, Fletcher GH. Analysis of the parameters relating to failures above the clavicles in patients treated by postoperative irradiation for squamous cell carcinoma of the oral cavity or oropharynx. Int J Radiat Oncol Biol Phys. 1982;8:27–30.

    Google Scholar 

  2. Ang KK, Trotti A, Brown BW, et al. Randomized trial addressing risk features and time factors of surgery plus radiotherapy in advanced head-and-neck cancer. Int J Radiat Oncol Biol Phys. 2001;51:571–8.

    Article  PubMed  CAS  Google Scholar 

  3. Pignon JP, Bourhis J, Domenge C, Designe L. Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. MACH-NC Collaborative Group. Meta-Analysis of Chemotherapy on Head and Neck Cancer. Lancet. 2000;355:949–55.

    PubMed  CAS  Google Scholar 

  4. Cooper JS, Pajak TF, Forastiere AA, et al. Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck. N Engl J Med. 2004;350:1937–44.

    Article  PubMed  Google Scholar 

  5. Bernier J, Domenge C, Ozsahin M, et al. Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck Cancer. N Engl J Med. 2004;350:1945–52.

    Article  PubMed  CAS  Google Scholar 

  6. Awwad HK, Lotayef M, Shouman T, et al. Accelerated hyperfractionation (AHF) compared to conventional fractionation (CF) in the postoperative radiotherapy of locally advanced head and neck cancer: influence of proliferation. Br J Cancer. 2002;86:517–23.

    Article  PubMed  CAS  Google Scholar 

  7. Bonner JA, Harari P, Giralt J, et al. Cetuximab (erbituxTM) prolongs survival in patients with locally advanced squamous cell carcinoma of the head and neck: A phase III study of high dose radiation therapy with or without cetuximab. J Clin Oncol. 2004;22: Suppl 14; S489. Abstract 5507.

  8. Reyes López V, Navalpotro Yagüe B. Adjuvant treatment of locally-advanced head and neck tumours. Clin Transl Oncol. 2005;7:183–8.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Giralt, J., Bernier, J. Postoperative radiotherapy with simultaneous chemotherapy in high-risk squamous cell carcinoma of the head and neck: a novel standard that opens new questions. Clin Transl Oncol 7, 181–182 (2005). https://doi.org/10.1007/BF02712814

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02712814

Navigation