Journal of Chemical Sciences

, Volume 115, Issue 5–6, pp 703–709 | Cite as

Ciprofloxacin@SiO2: Fluorescent nanobubbles

  • M. J. Rosemary
  • V. Suryanarayanan
  • P. Ganapatireddy
  • Ian Maclaren
  • S. Baskaran
  • T Pradeep


We report a new nanomaterial in which ciprofloxacin molecules are incorporated inside silica nanobubbles, denoted as ciprofloxacin@SiO2. The material has been characterised using UV/Vis absorption spectroscopy, transmission electron microscopy, cyclic voltammetry, and emission spectroscopy. The material is stable and the freestanding particles can be precipitated and redispersed in several solvents. Confinement of the molecule is complete as leaching through the shell is minimal. The material behaves like free ciprofloxacin in solution; however, effects of confinement are manifested. Energy transfer reaction between ciprofloxacin@SiO2 and Tb3+ was monitored by emission spectroscopy. The emission intensity decreased with metal ion exposure indicating selective electronic interaction.


Ciprofloxacin SiO2 nanobubble Tb3+ fluorescence 


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Copyright information

© Indian Academy of Sciences 2003

Authors and Affiliations

  • M. J. Rosemary
    • 1
    • 2
  • V. Suryanarayanan
    • 1
    • 2
  • P. Ganapatireddy
    • 1
  • Ian Maclaren
    • 3
  • S. Baskaran
    • 1
  • T Pradeep
    • 1
    • 2
  1. 1.Department of ChemistryIndian Institute of Technology MadrasChennaiIndia
  2. 2.Regional Sophisticated Instrumentation CentreIndian Institute of Technology MadrasChennaiIndia
  3. 3.Darmstadt University of TechnologyInstitute for Materials ScienceDarmstadtGermany

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