References
Adamian L, Nanda V, DeGrado W F and Liang J 2005 Empirical lipid propensities of amino acid residues in multispan alpha helical membrane proteins;Proteins 59 496–509
Andersen O S, Greathouse D V, Providence L L, Becker M D and Koeppe R E 1998 Importance of tryptophan dipoles for protein function: 5-fluorination of tryptophans in gramicidin A channels;J. Am. Chem. Soc. 120 5142–5146
Anderson D G, Shirts R B, Cross T A and Busath D D 2001 Noncontact dipole effects on channel permeation. V. Computed potentials for fluorinated gramicidin;Biophys. J. 81 1255–1264
Becker M D, Greathouse D V, Koeppe R E and Andersen O S 1991 Amino acid sequence modulation of gramicidin channel function: effects of tryptophan-to-phenylalanine substitutions on the single-channel conductance and duration;Biochemistry 30 8830–8839
Chattopadhyay A 2003 Exploring membrane organization and dynamics by the wavelength-selective fluorescence approach;Chem. Phys. Lipids 122 3–17
Chattopadhyay A and Kelkar D A 2005 Ion channels and D-amino acids;J. Biosci. 30 147–149
Chiang C-S, Shirinian L and Sukharev S 2005 Capping transmembrane helices of MscL with aromatic residues changes channel response to membrane stretch;Biochemistry 44 12589–12597
de Planque M R R, Boots J-W P, Rijkers D T S, Liskamp R M J, Greathouse D V and Killian J A 2002 The effects of hydrophobic mismatch between phosphatidylcholine bilayers and transmembrane α-helical peptides depend on the nature of interfacially exposed aromatic and charged residues;Biochemistry 41 8396–8404
Domene C, Vemparala S, Klein M L, Vénien-Bryan C and Doyle D A 2006 Role of aromatic localization in the gating process of a potassium channel;Biophys. J. 90 L01-L03
Doyle D A, Cabral J M, Pfuetzner R A, Kuo A, Gulbis J M, Cohen S L, Chait B T and MacKinnon R 1998 The structure of the potassium channel: molecular basis of K+ conduction and selectivity;Science 280 69–77
Draheim R R, Bormans A F, Lai R Z and Manson M D 2005 Tryptophan residues flanking the second transmembrane helix (TM2) set the signaling state of the Tar chemoreceptor;Biochemistry 44 1268–1277
Edidin M 2003 Lipids on the frontier: a century of cell-membrane bilayers;Nat. Rev. Mol. Cell Biol. 4 414–418
Fonseca V, Daumas P, Ranjalahy-Rasoloarijao L, Heitz F, Lazaro R, Trudelle Y and Andersen O S 1992 Gramicidin channels that have no tryptophan residues;Biochemistry 31 5340–5350
Ippolito J A, Alexander R S and Christianson D W 1990 Hydrogen bond stereochemistry in protein structure and function;J. Mol. Biol. 215 457–471
Killian J A 1992 Gramicidin and gramicidin-lipid interactions;Biochim. Biophys. Acta 1113 391–425
Kuo A, Domene C, Johnson L N, Doyle D A and Vénien-Bryan C 2005 Two different conformational states of the KirBac3.1 potassium channel revealed by electron crystallography;Structure 13 1463–1472
Luecke H, Schobert B, Richter H-T, Cartailler J-P and Lanyi J K 1999 Structural changes in bacteriorhodopsin during ion transport at 2 angstrom resolution;Science 286 255–261
Miller A S and Falke J J 2004 Side chains at the membrane-water interface modulate the signaling state of a transmembrane receptor;Biochemistry 43 1763–1770
Perochon E, Lopez A and Tocanne J F 1992 Polarity of lipid bilayers: a fluorescence investigation;Biochemistry 31 7672–7282
Raghuraman H, Kelkar D A and Chattopadhyay A 2005 Novel insights into protein structure and dynamics utilizing the red edge excitation shift approach; inReviews in fluorescence, 2005 (eds) C D Geddes and J R Lakowicz (New York: Springer) vol. 2, pp 199–222
Rawat S S, Kelkar D A and Chattopadhyay A 2004 Monitoring gramicidin conformations in membranes: a fluorescence approach;Biophys. J. 87 831–843
Reithmeier RAF 1995 Characterization and modeling of membrane proteins using sequence analysis;Curr. Opin. Struct. Biol. 5 491–500
Schirmer T, Keller T A, Wang Y F and Rosenbusch J P 1995 Structural basis for sugar translocation through maltoporin channels at 3.1 Å resolution;Science 267 512–514
Seelig J 1977 Deuterium magnetic resonance: theory and application to lipid membranes;Q. Rev. Biophys. 10 353–418
Shank L P, Broughman J R, Takeguchi W, Cook G, Robbins A S, Hahn L, Radke G, Iwamoto T, Schultz B D and Tomich J M 2006 Redesigning channel-forming peptides: amino acid substitutions that enhance rates of supramolecular self-assembly and raise ion transport activity;Biophys. J. 90 2138–2150
White S H and Wimley W C 1994 Peptides in lipid bilayers: structural and thermodynamic basis for partitioning and folding;Curr. Opin. Struct. Biol. 4 79–86
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Kelkar, D.A., Chattopadhyay, A. Membrane interfacial localization of aromatic amino acids and membrane protein function. J. Biosci. 31, 297–302 (2006). https://doi.org/10.1007/BF02704101
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DOI: https://doi.org/10.1007/BF02704101