Abstract
The epididymis is an ideal extragonadal target site to inhibit fertility in the male. Synthesis and secretion of constituents like sialic acids, protein and glycerylphosphoryl choline by the epididymal epithelium under androgen control provide an ideal fluid environment for sperm maturation. An optimal level of sialic acid secretion by the epididymal epithelium is needed to maintain functional integrity of sperm. The existence of specific androgen receptors in the epididymis and spermatozoa are related to their ability to metabolise androgens.
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Abbreviations
- GPC:
-
glycerylphosphoryl choline
- DHT:
-
dihydrotestosterone
- M r :
-
molecular weight
References
Anand Kumar, T. C., Prakash, A. and Prasad, M. R. N. (1980)Anat. Anz.,147, 220.
Bedford, J. M. (1965)J. Anat.,99, 891.
Bedford, J. M. and Cooper, G. W. (1978) inMembrane Fusion (ed G. Poste, and G. L. Nicolson), (Elsevier/North Holland Biomedical Press, Amsterdam), 65.
Blaquier, J. A. and Calandra, R. S. (1973)Endocrinology,93, 51.
Bose, T. K., Prasad, M. R. N. and Moudgal, N. R. (1975)Indian J. Exp. Biol.,13, 8.
Cheng, C. Y., Boettcher, B., Rose, R. J., Kay, D. J. and Tinneberg, H. R. (1981a)Int. J. Androl.,4, 1.
Cheng, C. Y., Rose, R. J. and Boettcher, B. (1981b)Int. J. Androl.,4, 304.
Dinakar, N., Arora, R. and Prasad, M. R. N. (1974a)J. Endocrinol.,60, 399.
Dinakar, N., Arora, R. and Prasad, M. R. N. (1974b)Int. J. Fertil.,19, 133.
Gloyna, R. E. and Wilson, J. D. (1969)J. Clin. Endocrinol.,29, 970.
Gupta, G., Rajalakshmi, M. and Prasad, M. R. N. (1974)Steroids,24, 575.
Gupta, G., Rajalakshmi, M., Prasad, M. R. N. and Moudgal, N. R. (1974)Contraception,10, 491.
Hammerstedt, R. H. and Amann, R. P. (1976)Biol. Reprod.,15, 686.
Hoffer, A. P. and Hinton, B. T. (1984)Biol. Reprod.,30, 991.
Holt, W. V. (1980)Biol. Reprod.,23, 847.
Howards, S., Lechene, C. and Vigersky, R. (1979) inThe Spermatozoon, (eds D. W. Fawcett and J. M. Bedford) (Baltimore-Munich: Urban and Schwarzenberg), p. 35.
Karkun, T., Rajalakshmi, M. and Prasad, M. R. N. (1974)Contraception,9, 471.
Koehler, J. K. (1981)Arch. Androl.,6, 197.
Nicolson, G. L., Usui, N., Yanagimachi, R., Yanagimachi, H. and Smith, J. R. (1977)J. Cell Biol.,74, 950.
Prasad, M. R. N. and Rajalakshmi, M. (1976)Gen. Comp. Endocrinol.,28, 530.
Rajalakshmi, M. (1984)Arch. Andol., (in press)
Rajalakshmi, M., Arora, R., Bose, T. K., Dinakar, N., Gupta, G., Thampan, T. N. R. V., Prasad, M. R. N., Anand Kumar, T. C. and Moudgal, N. R. (1976)J. Reprod. Fert. Suppl.,24, 71.
Rajalakshmi, M., Reddy, P. R. K. and Prasad, M. R. N. (1973)J. Endocrinol.,58, 349.
Rajalakshmi, M., Reddy, P. R. K., Prasad, M, R. N., Upadhyaya, P. and Minocha, V. R. (1975)Contraception,12, 175.
Rajalakshmi, M. and Prasad, M. R. N. (1968)J. Endocrinol.,41, 471.
Rajalakshmi, M. and Prasad, M. R. N. (1969)J. Endocrinol.,44, 379.
Rajalakshmi, M. and Prasad, M. R. N. (1976)Metabolism of testosterone by the accessory organs of the rat and its inhibition by cyproterone acetate, presented at V Internat. Congr. Endocrinology, Hamburg.
Rajalakshmi, M. and Prasad, M. R. N. (1977) inReproductive Physiology, (ed. R. O. Greep) (Baltimore University Park Press) p. 153.
Rajalakshmi, M., Leask, J. T. S. and Waites, G. M. H. (1978)Steroids,31, 747.
Rajalakshmi, M., Sehgal, A., Pruthi, J. S. and Anand Kumar, T. C. (1983)Steroids,41, 587.
Seamark, R. F. and White, I. G. (1964)J. Endocrinol.,30, 307.
Singh, R., Rajalakshmi, M. and Prasad, M. R. N. (1977)Indian J. Exp. Biol.,15 825.
Towicharanont, P. and Chulavatnatol, M. (1983)J. Reprod. Fert.,67, 275.
Wong, P. Y. D., Tsang, A. Y. F. and Lee, W. M. (1981)Int. J. Androl.,4, 331.
Wong, P. Y. D., Tsang, A. Y. G. and Wang, C. (1982)J. Androl.,3, 6.
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Rajalakshmi, M. Physiology of the epididymis and spermatozoa. J Biosci 7, 191–195 (1985). https://doi.org/10.1007/BF02703587
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DOI: https://doi.org/10.1007/BF02703587