Abstract
Bacitracin was more growth-inhibitory toNeurospora crassa on a minimal magnesium medium than on a normal magnesium-medium. Both magnesium and manganese were able to counteract the growth inhibition. The antifungal activity of bacitracin was potentiated by zinc. Potassium could not counteract the growth inhibition by this antibiotic. The mycelial magnesium levels were low in bacitracin-inhibited cultures.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Adiga, P. R., Sivarama Sastry, K., Venkatasubramanyam, V. and Sarma, P. S. (1961)Biochem. J.,81, 545.
Adler, R. H. and Snoke, J. E. (1962)J. Bacteriol.,83, 1315.
Anker, H. S., Johnson, B. A., Goldberg, J. and Meleney, F. L. (1948)J. Bacteriol.,55, 249.
Al-Saqur, A. (1975)Neurospora News Lett.,22, 6.
Block, W. D., Hubbard, R. W. and Westhoff, M. H. (1966)J. Chromatogr.,22, 391.
Chalmers, J. H. (1974)Neurospora News Lett.,21, 20.
Garbutt, J. T., Morehouse, A. L. and Hanson, A. M. (1961)J. Agric. Food. Chem.,9, 285.
Gross, H. M., Johnson, Wm. A. and Lafferty, G. J. (1954)J. Am. Pharm. Assoc,45, 447.
Haavik, H. 1. (1976)J. Gen. Microbiol.,96, 393.
Hancock, R. and Fitz-James, P. C. (1964)J. Bacteriol.,87, 1044.
Sharp, V. E., Arriagada, A., Newton, G. G. F. and Abraham, E. P. (1949)J. Exp. Pathol.,30, 444.
Sivarama Sastry, K., Adiga, P. R., Venkatasubramanyam, V., Sarma, P. S. (1962)Biochem. J. 85, 486.
Sivarama Sastry, K., Padmanabhan, G., Adiga, P. R. and Sarma, P. S. (1963)Analyst,88, 534.
Venkateswerlu, G. and Sivarama Sastry, K. (1973)Biochem. J.,132, 673.
Weinberg, E. D. (1958)Am. J. Clin. Pathol.,30, 344.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Venkateswerlu, G. Antifungal activity of bacitracin and its interaction with metals. J Biosci 3, 1–5 (1981). https://doi.org/10.1007/BF02703340
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/BF02703340