Abstract
A mathematical model of temperature modes in photodynamic therapy of brain tumors is suggested. Technological conditions for this therapy under which destruction of malignant cells along with photoprocesses are accompanied by hyperthermal and thermotherapeutic temperatures are determined. The realized possibilities allow one to achieve a higher degree of tumor destruction especially for low-perfusion tumors, with nearby healthy tissue being preserved.
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References
A. A. Krasnovskii,Advances in Science and Technology, Modern Problems of Laser Physics, Vol. 3 [in Russian], Moscow (1990), pp. 63–135.
I. S. Mel’nik, N. I. Bogachkov, and V. D. Rozumenko,Techniques and Methodology of Photodynamic Therapy [in Russian], Vols. 1–2, Kiev (1995). Deposited at State Scientific Engineering Library of Ukraine, No. 1971Uk95; No. 1972Uk95.
Z. P. Shul’man, B. M. Khusid, and I. V. Fain,Inzh.-Fiz. Zh.,68, No. 1, 75–85 (1995).
E. B. Chernyaeva, N. V. Stepanova, and L. L. Litinskaya,Advances in Science and Technology, Modern Problems of Laser Physics, Vol. 3 [in Russian], Moscow (1990), pp. 136–224.
B.W. Henderson, S. M. Waldow, W. P. Potter, and T. J. Dougherty,Cancer Research,45, 6071–6077 (1985).
J. Frietas, P. Pontiggia, F. Baronzio, and J. R. McZaren,Adv. Exp. Med. Biol.,267, 511–520 (1990).
L. O. Svaasand, Ch. J. Gomer, and E. Morinelli,Future Directions and Applications in Photodynamic Therapy. SPIE Institute Series,IS6, 233–248 (1990).
L. I. Grossweiner,Laser in Surgery and Medicine,11, 165–173 (1991).
Yu. A. Zosulya,Blood Circulation in Tumors of Brain Hemispheres [in Russian], Kiev (1972).
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Bidnenko, V.N., Sigal, V.L. Thermophysical effects in photodynamic tumor therapy. J Eng Phys Thermophys 72, 915–919 (1999). https://doi.org/10.1007/BF02699415
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DOI: https://doi.org/10.1007/BF02699415