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Tic douloureux, Parkinson’s disease and the herpes connection

  • James S. Howard
Papers

Abstract

Several cases encountered in psychiatric practice are described in which herpetic involvement of the trigeminal nerve appeared to be crucial to the pathophysiology of the patients’s illness. A brief history of herpes is discussed in terms of the anatomy and physiology of the trigeminal nerve. Particular attention is given to the effects of intraneuronal herpes on gasserian ganglion and spinal nuclei discharge threshoolds, as well as viral pathways directly impacting the substantia nigra. Evidence characterizing Parkinson’s disease as one of several important manifestations of CNS herpes is covered.

Keywords

Herpes Simplex Type Herpes Zoster Acyclovir Trigeminal Nerve Parkinsonian Symptom 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer 1996

Authors and Affiliations

  • James S. Howard
    • 1
  1. 1.Mental Health UnitSouthland HospitalInvercargillNew Zealand

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