Abstract
In patients with skin melanoma and colon cancer, cell distribution by the number of chromosome aberrations cannot be described by Poisson distribution, but corresponds to a bipopulation model combining the Poisson and geometric distributions. In contrast to the control, in patients with malignant tumors, cells with geometric distribution possess the majority of chromosomal aberrations.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
N. P. Bochkov, N. A. Popova, L. D. Katosova,et al., Genetika,35, No. 5, 735–742 (1999).
E. V. Domracheva, S. A. Kuznetsov, E. N. Shklovskii-Kordi, and A. I. Vorob’ev,Gematol. Transfuziol., No. 11, 36–37 (1991).
M. A. Pilinskaya, M. M. Shemetun, S. S. Dybskii,et al., Tsitol. Genetika,28, No. 1, 27–32 (1994).
O. I. Sokova, O. P. Kirichenko, O. E. Kulagina,et al., Genetika,33, No. 9, 1297–1302 (1997).
G. Korn and T. Korn,Mathematics Handbook for Researchers and Engineers, Moscow (1968).
A. N. Chebotarev,Dokl. Ros. Akad. Nauk,371, No. 6, 847–849 (2000).
A. V. Sevan’kaev, A. F. Tsyb., D. C. Lloyd,et al., Int. J. Radiat. Biol.,63, No. 3, 361–367 (1993).
S. Heim and F. Mitelman,Cancer Cytogenetics, N.Y. (1995).
J. V. Neel, A. A. Awa, Y. Kodama,et al., Proc. Natl. Acad. Sci. USA,89, 6973–6977 (1992).
Author information
Authors and Affiliations
Additional information
Translated fromByulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 130, No. 11, pp. 574–576, November, 2000
Rights and permissions
About this article
Cite this article
Chebotarev, A.N., Kirichenko, O.P. & Sokolova, O.I. Quantitative estimation of chromosome aberration frequency in cancer patients induced by endogenous and exogenous factors. Bull Exp Biol Med 130, 1106–1108 (2000). https://doi.org/10.1007/BF02688192
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02688192