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Delayed behavioral effects of β-casomorphin-7 depend on age and gender of albino rat pups

  • Physiology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Systemic administration of β-casein heptapeptide β-casomorphin-7 (YPFPGPI, 1 mg/kg daily) to 10–23-day-old albino rat pups produced delayed anxiolytic effects, which were more pronounced in female than in male rats. Experimental findings confirm our assumption on the important role of nutritional opioids in brain development in newborn mammals.

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Authors and Affiliations

  1. Department of Human and Animal Physiology, Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia

    V. A. Dubynin, I. V. Malinovskaya, Y. A. Ivleva, L. A. Andreeva, A. A. Kamenskii & I. P. Ashmarin

Authors
  1. V. A. Dubynin
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  2. I. V. Malinovskaya
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  3. Y. A. Ivleva
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  4. L. A. Andreeva
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  5. A. A. Kamenskii
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  6. I. P. Ashmarin
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Corresponding author

Correspondence to V. A. Dubynin.

Additional information

Translated fromByulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 130, No. 11, pp. 488–492, November, 2000

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Dubynin, V.A., Malinovskaya, I.V., Ivleva, Y.A. et al. Delayed behavioral effects of β-casomorphin-7 depend on age and gender of albino rat pups. Bull Exp Biol Med 130, 1031–1034 (2000). https://doi.org/10.1007/BF02688170

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  • DOI: https://doi.org/10.1007/BF02688170

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