Abstract
For electronic microscopic observation, we found SSV-transformed NIH 3T3 cells were different from non-transformed cells. In SSV-transformed NIH 3T3 cells nuclei/cytoplasma ratio was increased and in cytoplasma the ribosomes (polyribosomes were attached to the swollen rough endoplasmic reticulum. It was likely that ribosomes were lined together functionally and structionally to produce specific protein (PDGF-like protein).
Similar content being viewed by others
References
Deuel T.F, et al. Expression of a platelet-derived growth factor-like protein in simian sarcoma virus transformed cells. Science 1983; 221:138.
Antoniades H.N. Platelet-derived growth factor and malignant transformation. Biochem Pharmacol 1984; 33:2823.
Fry D.G, et al. Transformation of diploid human fibroblasts by DNA transfection with the v-sis oncogene. J Cellul Physiol 1986; 128:313.
Su S.Y. Electron microsocopic observation on the distribution of ACPase in esophageal cancer epithelial cells (ECa109) treated by vincrestine. Chin J Phys Med 1987; 9(2):103.
Su S.Y, Liu Y. Electron microscopic observation of gossypol effects on gastrocnemius muscles in laboratory animals. Proc CAMS and PUMC 1987; 2:98.
Tian J. S. V-sis transformed NIH 3T3 cells in serum-free medium. 1989 (In press).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Tian, J., Su, S. Electron microscopic observation of simian sarcoma virus transformed NIH 3T3 cells in vitro. Chinese Journal of Cancer Research 1, 13–15 (1989). https://doi.org/10.1007/BF02684810
Issue Date:
DOI: https://doi.org/10.1007/BF02684810