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Antioxidant activity of parapharmaceutics containing natural inhibitors of free radical processes

  • Biophysics and Biochemistry
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The duration of lag phase of ascorbate-dependent free radical oxidation of endogenous polyenic lipids in rat liver and myocardium considerably increased after oral administration of lacrinat containing licoriceGlycyrrhiza glabra root powder for 1 month. Lacrinat markedly decreased the content of lipid peroxides in rat liver.Ex vivo antioxidant effects of lacrinat in rat liver were comparable with those of β-carotene-containing preparations carinat and carinat CD. Parapharmaceutics containing both licoriceGlycyrrhiza glabra root powder and β-carotene (carinat forte) markedly increased antioxidant activity of the liver.

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Authors and Affiliations

  1. Laboratory of Biochemistry of Free Radical Processes, Russian Cardiology Research-and-Production Center, Russian Ministry of Health, Moscow

    G. G. Konovalova, A. K. Tikhaze & V. Z. Lankin

  2. A.L. Myasnikov Institute of Cardiology, Russian Cardiology Research-and-Production Center, Russian Ministry of Health, Moscow

    G. G. Konovalova, A. K. Tikhaze & V. Z. Lankin

Authors
  1. G. G. Konovalova
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  2. A. K. Tikhaze
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  3. V. Z. Lankin
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 130, No. 7, pp. 56–58, July, 2000

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Konovalova, G.G., Tikhaze, A.K. & Lankin, V.Z. Antioxidant activity of parapharmaceutics containing natural inhibitors of free radical processes. Bull Exp Biol Med 130, 658–660 (2000). https://doi.org/10.1007/BF02682098

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  • DOI: https://doi.org/10.1007/BF02682098

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