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Bronchoalveolar lavage cells and mitotic activity of monocytes and macrophages in rats after long-term intermittent hypoxia

  • General Pathology and Pathological Physiology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Long-term (1.5 months) intermittent hypoxia promoted desquamation of bronchial epithelial cells, decreased the relative content of alveolar macrophages and monocytes in bronchoalveolar lavage, stimulated lymphocyte migration to the lungs, and increased the relative content of lymphoid cell in rats. Mitotic activity of monocytes and macrophages decreased against the background of intraalveolar lymphocytosis (lymphocytic alveolitis).

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References

  1. A. P. Avtsyn, G. I. Lukomskii, L. K. Romanova,et al., Sov. Med., No. 7, 8–14 (1982).

    PubMed  Google Scholar 

  2. O. V. Aleksandrov, R. S. Vinnitskaya, E. G. Davydov, and P. V. Struchkov,Ter. Arkh., No. 3, 96–99 (1991).

    Google Scholar 

  3. G. A. Dobrovol'skii, A. P. Milovanov, and A. K. Karabaeva,Hypoxic Lung. Postadaptation [in Russian], Saratov (1992).

  4. O. V. Makarova,Morphological Principles of Lung Reactivity during Adaptation to Hypoxia and Inflammatory Processes, Abstract of Doct. Med. Sci. Dissertation, Moscow (1997).

  5. O. V. Makarova, L. P. Mikhailova, A. S. Sladkopevtsev,et al., Pul'monologiya, No. 4, 35–39 (1992).

    Google Scholar 

  6. M. G. Matveev,Clinical and Biochemical Signs of the Efficiency of Hypoxic Treatment of Patients with Bronchial Asthma and Chronic Obstructive Bronchitis, Abstract of Cand. Med. Sci. Dissertation, Moscow (1997).

  7. F. Z. Meerson,Adaptation, Stress, and Prophylaxis [in Russian], Moscow (1981).

  8. M. M. Mirrakhimov,Bronchial Asthma and Therapy with Hypobaric Hypoxia [in Russian], Leningrad (1983).

  9. N. P. Mikhailova, O. V. Makarova, A. S. Sladkopevtsev, and I. E. Zykova,Arkh. Pat., No. 3, 68–71 (1994).

    Google Scholar 

  10. L. K. Romanova, ——Ibid.,, No. 11, 22–27 (1991).

    Google Scholar 

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Authors and Affiliations

  1. Laboratory of Pulmonology, Institute of Human Morphology, Russian Academy of Medical Sciences, Moscow

    L. K. Romanova & L. F. Makarova

Authors
  1. L. K. Romanova
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  2. L. F. Makarova
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 130, No. 10, pp. 388–390, October, 2000

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Romanova, L.K., Makarova, L.F. Bronchoalveolar lavage cells and mitotic activity of monocytes and macrophages in rats after long-term intermittent hypoxia. Bull Exp Biol Med 130, 945–947 (2000). https://doi.org/10.1007/BF02682033

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  • DOI: https://doi.org/10.1007/BF02682033

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