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Role of thyroid hormones in stress-induced synthesis of heat-shock proteins in the myocardium

  • General Pathology and Pathological Physiology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Thyroxine in near-physiological doses increased the content of heat-shock proteins in the myocardium and stimulated their accumulation during immobilization stress. Blockade of thyroid functions with methimazole decreased the content of heat-shock proteins in rat myocardium during stres and heat shock and prevented their accumulation during adaptation to short-term immobilizations.

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Authors and Affiliations

  1. Laboratory of Molecular Mechanisms of Adaptation, Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow

    L. Yu. Bakhtina & I. Yu. Malyshev

  2. Department of Normal Physiology, Medical University, Vitebsk

    I. V. Gorodetskaya & A. P. Bozhko

Authors
  1. I. V. Gorodetskaya
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  2. A. P. Bozhko
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  3. L. Yu. Bakhtina
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  4. I. Yu. Malyshev
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 130, No. 12, pp. 617–619, December, 2000

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Gorodetskaya, I.V., Bozhko, A.P., Bakhtina, L.Y. et al. Role of thyroid hormones in stress-induced synthesis of heat-shock proteins in the myocardium. Bull Exp Biol Med 130, 1138–1140 (2000). https://doi.org/10.1007/BF02682007

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  • DOI: https://doi.org/10.1007/BF02682007

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