Abstract
Single total hyperthemia changed the absolute number of cardiomyocytes in experimental animals. The total number of cardiomyocytes decreased by 20% (without signs of their necrosis) on day 3 of post-heating restitution and then returned to the control. This was probably related to cytokinesis (without karyokinesis) of binucleated cells, whose content considerably decreased during recovery.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 130, No. 8, pp. 228–231, August, 2000
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Lushinikova, E.L., Nepomnyashchikh, L.M., Molodykh, O.P. et al. Death, elimination, and regeneration of cardiomyocytes in mice after hyperthermia. Bull Exp Biol Med 130, 810–812 (2000). https://doi.org/10.1007/BF02681953
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DOI: https://doi.org/10.1007/BF02681953