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Anti–Inflammatory activity of a holothurian (sea cucumber) food supplement in rats

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Whitehouse MW, Fairlie DP. Anti-inflammatory activity of a holothurian (sea cucumber) food supplement in rats. Inflammopharmacology. 1994;2:411-417.

A human food supplement (SeaCare ) composed of dried extracts from specific varieties of holothurians (sea cucumbers) and a sea plant has been found to have anti-inflammatory activity in both sexes of two strains of rats. It is slightly less active than aspirin (w/w) against the acute carrageenan-induced paw inflammation, but without the gastrotoxicity of aspirin. It is also active against adjuvant-induced polyarthritis in rats on a daily dose schedule.

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Authors and Affiliations

  1. Department of Pathology, University of Adelaide, 5005, SA, Australia

    M. W. Whitehouse

  2. Centre for Drug Design and Development, University of Queensland, 4072, Brisbane, Queensland, Australia

    D. P. Fairlie

Authors
  1. M. W. Whitehouse
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  2. D. P. Fairlie
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Whitehouse, M.W., Fairlie, D.P. Anti–Inflammatory activity of a holothurian (sea cucumber) food supplement in rats. Inflammopharmacology 2, 411–417 (1994). https://doi.org/10.1007/BF02678607

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  • DOI: https://doi.org/10.1007/BF02678607

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