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Luminescence studies of porphyrin exchange in pregnant females

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Abstract

Results of investigations of the level of proto- and coporphyrins in erythrocytes and excretion of coproto- and uroporphyrins from the organism for two control groups are presented. The first group consisted of healthy males and females 20–33 years of age; the second group was consisted of females with nonpathological pregnancy. Levels of proto- and coporphyrins in erythrocytes and copro- and uroporphyrins in urine are investigated. A reliable (P<0.03) increase in the protoporphyrin concentration in erythrocytes of pregnant females compared to the first control group is found. The average protoporphyrin levels in the first and second groups are 344±18 and 488±20 μg/liter, respectively. Coporphyrin levels in these groups differ insignificantly. Coporphyrin excretion from the organism of pregnant females has shown a tendency to increase for pregnancy terms of up to eight weeks and decrease for long terms (more than 32 weeks).

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References

  1. L. I. Idel’son, Disorders of Porphyrin Exchange in Clinic [in Russian], Leningrad (1968) p. 183.

  2. N. P. Kuznetsova, B. S. Pankova, A. S. Chubarova, et al., Porphyrin [in Russian], Moscow (1981) p. 192.

  3. M. Doss (ed.), Porphyrins in Human Diseases, Based (1976), p. 512.

  4. Kh. A. Kakhn and V. I. Muzyka, Proceedings of the Symposium on Biomedical Aspects of Investigation and Applications of Porphyrins, Tallin (1989), p. 91.

  5. S. Hernberg and Kh. Kakhn (eds.), Papers Presented at the II Finnish-Estonian Symposium on Action of Toxic Substances, Helsinki (1981), p. 212.

  6. Yu. P. Evlashko, Porphyrin Metabolism in Occupational Diseases [in Russian], Moscow (1982), p. 12.

  7. A. M. Monaenkova, O. G. Arkhipova, L. A. Zorina, et al. Gigiena Truda,6, 11–15 (1982).

    Google Scholar 

  8. V. I. Muzyka, in: Proceedings of the I Symposium on Physiology and Pathology in Porphyrin and Heme Metabolism, Tallin (1974), pp. 38–30.

  9. T. T. Berezov and V. N. Popova, Clinical Biochemistry [in Russian], Moscow (1973), 290 p. 290.

  10. I. A. Magnus, Br. Med. J.,288, 1474–1475 (1984).

    Article  Google Scholar 

  11. L. A. Grubina, Porphyrin-Class Compounds in Diagnosis and Treatment of Oncological Diseases, Candidate’s Dissertation, Minsk (1990).

  12. G. P., Gurinovich, I. F. Gurinovich, S. I. Shishporenok, and E. P. Shmerko, in: Proceesings of the First Scientific and Practical Conference of the Scientific Research Institute of Radiation Medicine, Minsk (1991), pp. 47–49.

  13. G. P. Gurinovich, A. E. Okeanov, I. F. Gurinovich, et al. Terapevticheskii Arkhiv,63, 47–50 (1991).

    Google Scholar 

  14. I. F. Gurinovich, L. A. Grubina, S. F. Nekrashevich, et al., Voprosy Med. Khim.,5, 34–37 (1988).

    Google Scholar 

  15. K. K. Atanasov, M. P. Pisanets, and V. A. Vakrilov, Gematologiya Transfuziologiya31, 16–18 (1986).

    Google Scholar 

  16. I. F. Gurinovich, L. A. Grubina, L. A. Meleshchenko, and L. M. Vinnik, Zh. Prikl. Spektrosk.,61, 415–419 (1994).

    Google Scholar 

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Translated from Zhurnal Prikladnoi Spektroskopii, Vol. 64, No. 5, pp. 633–636, September–October, 1997.

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Grubina, L.A., Litvinovich, N.G. Luminescence studies of porphyrin exchange in pregnant females. J Appl Spectrosc 64, 646–649 (1997). https://doi.org/10.1007/BF02675326

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