Abstract
This paper resports the response of inoperable primary liver cancer to whole liver irradiation (WLI) by moving-strip technique (MST) during the period from 1980–1988. The results showed that WLI by MST gave good response in this malignancy. The 5-year survival after treatment was 30.83% and median survival 25.8 months. The analysis of prognostic factors indicated that the higher the midplane tissue dose (mTD), the longer the survival (P<0.001), and that the survival of those patients tumor diameter was >8 to <13 cm and/or tumor volume >50% to <75% of liver volume was longer than that of those with tumor diameter of ≥13 cm and/or tumor volume ≥75% of the liver volume (P<0.001). Traditional Chinese medicine is an indispensable therapy during the period of WLI by MST. Both clinical and experimental studies suggest that WLI by MST can enhance the therapeutic effect.
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References
Balsasegaram M. Management of primary liver cell carcinoma. Am J Surg 1975; 130: 33
Falkson G. Therapeutic approaches to hepatoma. Cancer Treat Rev 1975: 2: 73.
Nerenstone SR. Clinical trials in primary hepatocellular carcinoma: Current status and future directions. Cancer Treat Rev 1988; 15: 1.
Yu EX. Radiotherapy of primary liver cancer. Tang ZY, Wu MC, Xia SS, et al. eds. Primary liver cancer. Beijing: China Academic Publishers & Berlin: Springer-Verlag. 1989; 425–429.
Delclos L, Braun EJ, Herrera R, et al. Whole abdominal irradiation by Cobalt-60 movingstrip technic. Radiology 1963; 81: 632.
Liu LM, Yu EX. Treatment of pain according to syndrome differentiation in 169 cases of liver cancer. J. Trad Chin Med 1989; 9: 277.
Liu, F. Application of traditional Chinese drugs in comprehensive treatment of primary liver cancer. J Trad Chin Med 1990; 10: 54.
Peto R, Pike MC, Armitage P, et al. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. Part I: Analysis and Examples. Br J Cancer 1977; 35: 1.
Ingold J, Reed GB, Kaplan HS, et al. Radiation hepatitis. Am J Roentgenol 1965; 93: 200.
Phillips R, Murikami K. Primary neoplasms of the liver sults of radiation therapy. Cancer 1960, 13: 714.
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Erxin, Y., Luming, L., Mingzhi, S. et al. Clinical study on irradiation combined with traditional chinese medicine in the treatment of large primary liver cancer. Chinese Journal of Cancer Research 6, 63–68 (1994). https://doi.org/10.1007/BF02672264
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DOI: https://doi.org/10.1007/BF02672264