Abstract
Pituitary adenoma may be calssified in light of the hormones produced. 225 surgical specimens were labeled with anti-sear of GH, PRL. ACTH, TSH, FSH and LH by immunohistochemical technique (ABC method). Data indicated that 100 out of 225 cases (44.5%) were monohormonal adenomas, including 24 GH, 39 PRL, 1 FSH and 9 LH, 77 (34.2%) were multi-hormonal adenomas, including 28 positive for 2 hormones, 30 positive for 3 hormones, 19 positive for 4 or more different hormones, and the remaining 48 (21.3%) were nonfunctional adenomas. In comparison with Kovacs series, factors which might participate in the mechanism of developing monohormonal or multi-hormonal adenomas are discussed.
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Fulin, Z., Yulin, Z., Jinxiu, H. et al. Functional classification of pituitary adenoma. Chinese Journal of Cancer Research 3, 62–65 (1991). https://doi.org/10.1007/BF02672094
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DOI: https://doi.org/10.1007/BF02672094