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Observations on manganese-containing superoxide dismutase activity in human lung cancer

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Chinese Journal of Cancer Research

Abstract

Manganese-containing superoxide dismutase (Mn-SOD) activity in lung cancer tissues from 5 patients with pulmonary carcinoma were measured by the nitrite formation method, lipid peroxide (LPO) values being measured by spectrophotometry of thiobarbituric acid reaction. The results obtained show that Mn-SOD activity exhibits most evidently in lung cancer tissues, less evidently in peripheral tissues around the lung cancer, but the least in normal peripheral lung tissues, indicating a declined tendency as definitely proved by statistical treatment (P<0.01). In addition, LPO values are found to be lower in lung cancer tissues than those in normal peripheral tissues.

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Authors and Affiliations

  1. Department of Thoracic Surgery, PLA General Hospital, Beijing

    Jiang Chaoguang & Huang Xiaomai

  2. Department of Biochemistry, PLA General Hospital, Beijing

    Shen Wenmei, Zhao Houan & Fang Erniu

Authors
  1. Jiang Chaoguang
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  2. Huang Xiaomai
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  3. Shen Wenmei
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  4. Zhao Houan
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  5. Fang Erniu
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Chaoguang, J., Xiaomai, H., Wenmei, S. et al. Observations on manganese-containing superoxide dismutase activity in human lung cancer. Chinese Journal of Cancer Research 3, 39–41 (1991). https://doi.org/10.1007/BF02672088

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  • DOI: https://doi.org/10.1007/BF02672088

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