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Morphological study of resected mitral and aortic valves in rheumatic heart disease

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Indian Journal of Thoracic and Cardiovascular Surgery Aims and scope Submit manuscript

Abstract

Gross and histological changes in simultaneously resected mitral and aortic valves in patients with rheumatic heart disease are described. All the mitral valves showed characteristic postinflammatory changes. However, 14 per cent of the resected aortic valves did not show features indicative of postinflammatory pathology and were considered to be only haemodynamically altered valves. Myxoid change seen in these valves was at times indistin-guishable from that seen in primary myxoid change in the valves. Our findings indicate that histological features in rheumatic involvement of the valve although suggestive are not diagnostic. Critical gross examination along with histological features will give aetiological diagnosis in most of the cases.

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References

  1. Waller BF, Morgan RD, Iron M, Miller JM, Debruler RO. General concepts in the morphological evaluation of operatively excised valves In Waller BF,et al.Pathology of the heart and great vessels. New York: Churchill Livingstone 1988:1–42.

    Google Scholar 

  2. Vander Bel-kahn J, Becker AE. The surgical pathology of rheumatic and floppy mitral valves. Distinctive morphological features upon gross examination.Am J Surg Pathol 1986: 10:282–92.

    Article  PubMed  Google Scholar 

  3. Edwards JE. Pathology of mitral incompetenceIn Silver EMD, ed.Cardiovascular Pathology Vol 1. New York, Churchill Livingstone.

  4. Olsen EG1 Rheumatic heart disease InPathology of the heart 2nd ed. London, MacMillan Press 1980: 145.

    Google Scholar 

  5. Goffin VA, Leclerc JL, Primo GC. Histopathology of aortic valve in patients with previous history of acute rheumatic fever. An analysis of 63 surgical specimens.Acta Cardiol 1984;39:329–39.

    PubMed  CAS  Google Scholar 

  6. Turri M, Thiene G, Bortolotti U, Mazzuco A, Galluci V. Surgical pathology of disease of the mitral valve, with specific reference to lesions promoting valvar incompetenceInt J Cardiol 1989;22:213–9.

    Article  PubMed  CAS  Google Scholar 

  7. Pomerance A. Acquired non-rheumatic valvular and endocardial pathology.Pathol Annu 1977;12:151–87.

    PubMed  Google Scholar 

  8. Read RC, Thal AP, Wendt VE. Symptomatic valvular myxomatous transformation (A floppy valve syndrome): a possible forme fruste of the Marfan's syndrome.Circulation 1965;32:897–910.

    PubMed  CAS  Google Scholar 

  9. Kern HW, Tucker BL, Myxoid change in cardiac valves. Pathological, clinical and ultrastructural studies.Am Heart J 1972;84:294–301.

    Article  PubMed  CAS  Google Scholar 

  10. Aslam PA, Estridge CE, Bernhardt H, Plate JW. Myxomatous degeneration of cardiac valves.Chest 1970;57:535–9.

    Article  PubMed  CAS  Google Scholar 

  11. Freble WJ. Mucinous degeneration of the cardiac valves-A floppy valve syndrome.J Thorac Cardiovas Surg 1969;58:62–70.

    Google Scholar 

  12. Bittar N, Sosa JAA. The ballooning mitral valve leaflet. Report on fourteen patients.Circulation 1968;38:763–70.

    PubMed  CAS  Google Scholar 

  13. Rippe J, Fishbein MC, Cerebello B,et al. Primary myxomatous degeneration of cardiac valves.Br Heart J 1980;44:621–9.

    Article  PubMed  CAS  Google Scholar 

  14. Pomerance A. Ageing and degenerative changes.In Pomerance A, Davis MJ, edsThe pathology of heart. London, Blackwall Scientific 1975: 47.

    Google Scholar 

  15. Roberts WC, Marrow AG. Cardiac valves and the surgical pathologists.Arch Pathol 1966;82:309–13.

    PubMed  CAS  Google Scholar 

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Malhotra, V., Tatke, M., Gondal, R. et al. Morphological study of resected mitral and aortic valves in rheumatic heart disease. Indian J Thorac Cardiovasc Surg 8, 45–48 (1992). https://doi.org/10.1007/BF02664124

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