Summary
Neuronal colonie dysplasia is a separate clinical entity belonging to the group of congenital defects of intestinal innervation. Its enzyme-histochemical diagnosis is possible by endoscopie biopsy examination of the rectosigmoid. Enzyme-histochemically, it is characterized by dysplasia of the submucous plexus secondary to developmental defects. The principal clinical feature is weak propulsive motility. A clinical study was carried out to investigate the role of neuronal colonie dysplasia in the aetiology and pathogenesis of primary chronic constipation and diverticulosis of the sigmoid colon in adults.
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Stoss, F., Meier-Ruge, W. Diagnosis of neuronal colonic dysplasia in primary chronic constipation and sigmoid diverticulosis —endoscopic biopsy and enzyme-histochemical examination. Surg Endosc 5, 146–149 (1991). https://doi.org/10.1007/BF02653223
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DOI: https://doi.org/10.1007/BF02653223