Skip to main content
SpringerLink
Log in

Interaction of gossypol with the ferrous ion

  • Published:
Journal of the American Oil Chemists Society

Summary

The preparation of a solution of sodium gossypolate in aqueous acetone has been described. Indications of a 1∶1 mole ratio combination of the gossypolate and ferrous ions were established through conductometric and potentiometric studies in the presence of either chloride or perchlorate anion. Application of the method of continuous variations to differences in the absorption spectra of the two species confirmed the 1∶1 mole ratio of ferrous ion to gossypol. This finding is supported by analytical data. Values of pK for the dissociation constant of ferrous gossypolate, calculated from spectrophotometric measurement, averaged 7.3.

Since the peri-hydroxyls are the most plausible location of the sodium ions in sodium gossypolate, its reaction with ferrous ion results in displacement of the two sodium ions by the ferrous ion.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Adams, R., Morris, R. C., Geissman, T. A., Butterbaugh, D. J., and Kirkpatrick, E. C., J. Am. Chem. Soc.,60, 2193–2204 (1938).

    Article  CAS  Google Scholar 

  2. Carruth, F. E., J. Am. Chem. Soc.,40, 647–663 (1918).

    Article  CAS  Google Scholar 

  3. Gallup, W. D., J. Biol. Chem.,77, 437–449 (1928).

    CAS  Google Scholar 

  4. Job, P., Ann. chim., [10]9, 113–203 (1928).

    CAS  Google Scholar 

  5. Marchlewski, L., J. prakt. Chem.,60, 84–90 (1899).

    Article  CAS  Google Scholar 

  6. Turner, S. E., and Anderson, R. C., J. Am. Chem. Soc.,71, 912–914 (1949).

    Article  CAS  Google Scholar 

  7. Withers, W. A., and Brewster, J. F., J. Biol. Chem.15, 161–166 (1913).

    CAS  Google Scholar 

  8. Withers, W. A., and Carruth, F. E., J. Agr. Research,5, 261–288 (1915).

    CAS  Google Scholar 

  9. Withers, W. A., and Carruth, F. E., J. Biol. Chem.,32, 245–257 (1917).

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Tulane University, New Orleans, Louisiana

    Hans B. Jonassen

  2. Southern Regional Research Laboratory, New Orleans, Louisiana

    Robert J. Demint

Authors
  1. Hans B. Jonassen
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Robert J. Demint
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Findings reported in this paper were included in a thesis submitted to Tulane University by Robert J. Demint in partial fulfillment of the requirements for the M.S. degree.

One of the laboratories of the Southern Utilization Research Branch, Agricultural Research Service, U. S. Department of Agriculture.

About this article

Cite this article

Jonassen, H.B., Demint, R.J. Interaction of gossypol with the ferrous ion. J Am Oil Chem Soc 32, 424–426 (1955). https://doi.org/10.1007/BF02639702

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02639702

Keywords

Search

Navigation