Skip to main content
SpringerLink
Log in

Necrotic dna degradation mimics apoptotic nucleosomal fragmentation comet tail length

  • Letter To The Editor
  • Published:
In Vitro Cellular & Developmental Biology - Animal Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Arends, M. J.; Morris, R. G.; Wyllie, A. H. Apoptosis: the role of endonucleases. Am. J. Pathol. 136:593–608; 1990.

    PubMed  CAS  Google Scholar 

  2. Brown, D. G.; Sun, X. M.; Cohen, G. M. Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation. J. Biol. Chem. 268:3037–3039; 1993.

    PubMed  CAS  Google Scholar 

  3. Cohen, G. M.; Sun, X. M.; Snowden, R. T., et al. Key morphologic features of apoptosis may occur in the absence of internucleosomal DNA fragmentation. Biochem. J. 286:331–334; 1992.

    PubMed  CAS  Google Scholar 

  4. Collins, R. J.; Harmon, R. V.; Gobé, G. C., et al. Internucleosomal DNA cleavage should not be the sole criterion for identifying apoptosis. Int. J. Rad. Biol. 61:451–453; 1992.

    PubMed  CAS  Google Scholar 

  5. Fairbairn, D. W.; O’Neill, K. L.; Standing M. D. Application of confocal laser scanning microscopy to analysis of H2O2-induced DNA damage in human cells. Scanning 15:136–139; 1993.

    PubMed  CAS  Google Scholar 

  6. Fairbairn, D. W.; Carnahan, K. G.; Thwaits, R. N., et al. Detection of apoptosis induced DNA cleavage in scrapie infected sheep brain. FEMS Microbiol. Lett. 115:341–346; 1994.

    Article  PubMed  CAS  Google Scholar 

  7. Fairbairn, D. W.; Reyes, W. A.; Grigsby, R. V., et al. Laser scanning microscopic analysis of DNA damage in frozen tissues. Cancer Lett. 76:127–132; 1994.

    Article  PubMed  CAS  Google Scholar 

  8. Kerr, J. F.; Wyllie, A. H.; Currie, A. R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26:239–257; 1972.

    PubMed  CAS  Google Scholar 

  9. Lockshin, R. A.; Alles, A.; Kodaman, N., et al. Programmed cell death and apoptosis: early DNA degradation does not appear to be prominent in either embryonic cell death or metamorphosis of insects. FASEB J. 5:A518; 1991.

  10. Olive, P. L.; Wlodek, D.; Durand, R. E., et al. Factors influencing DNA migration from individual cells subjected to gel electrophoresis. Exp. Cell Res. 198:259–267; 1992.

    Article  PubMed  CAS  Google Scholar 

  11. Olive, P. L.; Frazer, G.; Banath, J. P. Radiation-induced apoptosis measured in TK6 human B lymphoblast cells using the comet assay. Radiat. Res. 136:130–136; 1993.

    Article  PubMed  CAS  Google Scholar 

  12. Olive, P. L.; Chan, A. P. S.; Cu, C. S. Comparison between the DNA precipitation and alkali unwinding assays for detecting DNA strand breaks and cross-links. Cancer Res. 48:6444–6449; 1988.

    PubMed  CAS  Google Scholar 

  13. O’Neill, K. L.; Fairbairn, D. W.; Standing, M. D. Analysis of single cell gel electrophoresis using laser-scanning microscopy. Mutat. Res. 319:129–134; 1993.

    Article  PubMed  CAS  Google Scholar 

  14. Östling, O.; Johanson, J. P. Microelectrophoretic study of radiation-in-duced DNA damages in individual mammalian cells. Biochem. Biophys. Res. Commun. 123(1):291–298; 1984.

    Article  PubMed  Google Scholar 

  15. Östling, O.; Johanson, K. J. Bleomycin, in contrast to gamma irradiation, induces extreme variation of DNA strand breakage from cell to cell. Int. J. Radiat. Biol. 52(5):683–691; 1987.

    Google Scholar 

  16. Singh, N. P.; McCoy, M. T.; Tice, R. R., et al. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 175:184–191; 1988.

    Article  PubMed  CAS  Google Scholar 

  17. Uzawa, A.; Suzuki, G.; Nakata, Y., et al. Radiosensitivity of CD45RO+ memory and CD45RO− naive T cells in culture. Radiat. Res. 137: 25–33; 1994.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Microbiology 751 WIDB, Brigham Young University, 84602, Provo, Utah

    Dary W. Fairbairn & Kim L. O’Neill

Authors
  1. Dary W. Fairbairn
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Kim L. O’Neill
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Fairbairn, D.W., O’Neill, K.L. Necrotic dna degradation mimics apoptotic nucleosomal fragmentation comet tail length. In Vitro Cell Dev Biol - Animal 31, 171–173 (1995). https://doi.org/10.1007/BF02639429

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02639429

Keywords

Search

Navigation