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Biological vs. Chemical evaluation of toxicity and protein quality of cottonseed meals

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Journal of the American Oil Chemists Society

Summary

1. Toxicological evaluation of 68 cottonseed meals in rats failed to show a direct correlation between their toxicity and their free, total or combined gossypol content. The common practice of considering the free gossypol content of cottonseed meal as a yardstick for its toxicity is questioned.

2. There was poor correlation between biologically evaluated protein quality of cottonseed meals and their nitrogen solubility in 0.02N sodium hydroxide. Application of this chemical test for indicating the protein quality of cottonseed meals is likewise questioned on the basis of existing evidence.

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References

  1. Voelker, A., cited by Crawford, A. C., J. Pharmacol. Exp. Therap.,1, 519–48 (1910).

    Google Scholar 

  2. Withers, W. A., and Carruth, F. E., Science,41, 324 (1915).

    Article  CAS  Google Scholar 

  3. Withers, W. A., and Carruth, F. E., J. Agr. Res.,5, 261–88 (1915).

    CAS  Google Scholar 

  4. Withers, W. A. and Carruth, F. E., J. Agr. Res.,12, 83–102 (1918).

    CAS  Google Scholar 

  5. Carruth, F. E., J. Am. Chem. Soc.,40, 647–63 (1918).

    Article  CAS  Google Scholar 

  6. Longmore, J., J. Soc. Chem. Ind.,5, 200–6 (1886).

    Google Scholar 

  7. Marchlewski, L., J. für Prakt. Chem.,60, 80–90 (1899).

    Article  Google Scholar 

  8. Eagle, Edward, Bialek, H. F., Davies, D. L., and Bremer, J. W., J. Am. Oil Chemists’ Soc.,31, 121–4 (1954).

    Article  CAS  Google Scholar 

  9. Osborne, T. B., and Mendel, L. B., J. Biol. Chem.,37, 223–7 (1919).

    CAS  Google Scholar 

  10. Nevens, W. B., J. Dairy Sci.,4, 552–88 (1921).

    Article  CAS  Google Scholar 

  11. Mitchell, H. H., J. Biol. Chem.,58, 905–22 (1924).

    CAS  Google Scholar 

  12. Cahill, W. M., J. Am. Dietetic Asso.,21, 433–5 (1945).

    CAS  Google Scholar 

  13. Barnes, R. H., Bates, M. J., and Maack, J. E., J. Nutr.,32, 535–48 (1946).

    CAS  Google Scholar 

  14. Mitchell, H. H., J. Biol. Chem.,58, 873–903 (1924).

    CAS  Google Scholar 

  15. Carruth, F. E., J. Biol. Chem.,32, 87–90 (1917).

    CAS  Google Scholar 

  16. Reports of gossypol committees, A.O.C.S., Oil and Soap,23, 235–6 (1946); J. Am. Oil Chemists’ Soc.,24, 269–71 (1947);ibid., 25, 249–50 (1948);ibid., 27, 303 (1950).

  17. Panum, P., Arch. Path. Anat.,3, 251–64 (1851).

    Article  Google Scholar 

  18. Osborne, T. B., The Vegetable Proteins, Longmans, Green and Company, New York, 1918, p. 18.

    Google Scholar 

  19. Osborne, T. B., and Mendel, L. B., J. Biol. Chem.,29, 289–317 (1917).

    CAS  Google Scholar 

  20. Gallup, W. D., J. Biol. Chem.,76, 43–53 (1928).

    CAS  Google Scholar 

  21. Olcott, H. S., and Fontaine, T. D., J. Nutr.,22, 431–7 (1941).

    CAS  Google Scholar 

  22. Olcott, H. S., and Fontaine, T. D., Ind. Eng. Chem.,34, 714–16 (1942).

    Article  CAS  Google Scholar 

  23. Lyman, C. M., Chang, W. Y., and Couch, J. R., J. Nutr.,49, 679–90 (1953).

    CAS  Google Scholar 

  24. Pons, W. A., and Guthrie, J. D., J. Am. Oil Chemists’ Soc.,26, 671–6 (1949).

    CAS  Google Scholar 

  25. Pons, W. A., Hoffpauir, C. L., and O’Connor, R. T., J. Am. Oil Chemists’ Soc.,27, 390–3 (1950).

    CAS  Google Scholar 

  26. Eagle, Edward, Castillon, Leah E., Hall, C. M., and Boatner, Charlotte H., Arch. Biochem.,18, 271–7 (1948).

    CAS  Google Scholar 

  27. Eagle, Edward, Hall, C. M., Castillon, Leah E., and Miller, Charlotte B., J. Am. Oil Chemists’ Soc.,27, 300–3 (1950).

    CAS  Google Scholar 

  28. Eagle, Edward, and Bialek, H. F., Food Research,17, 543–9 (1952).

    CAS  Google Scholar 

  29. Schwartze, E. W., and Alsberg, C. L., J. Agr. Res.,25, 285–95 (1923).

    CAS  Google Scholar 

  30. Clark, E. P., J. Biol. Chem.,75, 725–39 (1927).

    CAS  Google Scholar 

  31. Clark, E. P., J. Biol. Chem.,76, 229–35 (1928).

    CAS  Google Scholar 

  32. Schwartze, E. W., and Alsberg, C. L., J. Agr. Res.,28, 173–98 (1924).

    CAS  Google Scholar 

  33. Clark, E. P., Nelson, E. M., and Jones, D. B., J. Oil and Fat Ind.,6 (7), 15–19 (1929).

    Article  CAS  Google Scholar 

  34. Nelson, E. M., and Jones, D. B., J. Biol. Chem.,87, xlvii (1930).

    Google Scholar 

  35. Lillie, R. J., and Bird, H. R., Poultry Sci.,29, 390–3 (1950).

    CAS  Google Scholar 

  36. Gallup, W. D., Ind. Eng. Chem.,20, 59–63 (1928).

    Article  CAS  Google Scholar 

  37. Boatner, Charlotte H., Altschul, A. M., Irving, G. W. Jr., Pollard, E. F., and Schaeffer, H. C., Poultry Sci.,27, 315–28 (1948).

    CAS  Google Scholar 

  38. Ambrose, A. M., and Robbins, D. J., J. Nutr.,43, 357–70 (1951).

    CAS  Google Scholar 

  39. Eagle, Edward, Bialek, H. F., Davies, D. L., and Bremer, J. W., to be published.

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Authors and Affiliations

  1. Research Laboratories, Swift and Company, Chicago, Illinois

    Edward Eagle, H. F. Blalek, D. L. Davies & J. W. Bremer

Authors
  1. Edward Eagle
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  2. H. F. Blalek
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  3. D. L. Davies
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  4. J. W. Bremer
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Eagle, E., Blalek, H.F., Davies, D.L. et al. Biological vs. Chemical evaluation of toxicity and protein quality of cottonseed meals. J Am Oil Chem Soc 33, 15–21 (1956). https://doi.org/10.1007/BF02638344

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  • DOI: https://doi.org/10.1007/BF02638344

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