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Synergistic inhibition of human rhabdomyosarcoma cells by sodium phenylacetate and tretinoin

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References

  1. Brusilow, S. W.; Danney, M.; Waber, L. J., et al. Treatment of episodic hyperammonemia in children with inborn errors of urea synthesis. N. Engl. J. Med. 310:1630–1634; 1984.

    Article  PubMed  CAS  Google Scholar 

  2. Crouch, G. D.; Helman, L. J. All-trans-retinoic acid inhibits the growth of human rhabdomyosarcoma cell lines. Cancer Res. 51:4882–4887; 1991.

    PubMed  CAS  Google Scholar 

  3. Elliott, S.; Taylor, K.; White, S., et al. Proof of differentiative mode of action of all-trans retinoic acid in acute promyelocytic leukemia using x-linked clonal analysis. Blood 79:1916–1919; 1992.

    PubMed  CAS  Google Scholar 

  4. Fischer, P. H.; Pamukcu, R.; Bittner, G., et al. Enhancement of the sensitivity of human colon cancer cells to growth inhibition by acivicin achieved through inhibition of nucleic acid precursor salvage by dipyridamole. Cancer Res. 44:3355–3359; 1984.

    PubMed  CAS  Google Scholar 

  5. Gabbert, H. E.; Gerharz, C. D.; Biesalski, H-K., et al. Terminal differentiation and growth inhibition of a rat rhabdomyosarcoma cell line (BA-HAN-IC) in vitro after exposure to retinoic acid. Cancer Res. 48:5264–5269; 1988.

    PubMed  CAS  Google Scholar 

  6. Gareval, H. S.; Meyskens, F., Jr. Retinoids and carotenoids in the prevention of oral cancer: a critical appraisal. Cancer Epidem. Biomarkers Prevent. 1:155–159; 1992.

    Google Scholar 

  7. Garvin, A. J.; Stanley, W. S.; Sullivan, J. L., et al. The in vitro growth, heterotransplantation, and differentiation of a human rhabdomyosarcoma cell line. Am. J. Pathol. 125:208–217; 1986.

    PubMed  CAS  Google Scholar 

  8. Goodwin, J. S.; Goodwin, J. M. The tomato effect. Rejection of highly efficacious therapies. JAMA 251:2387–2390; 1984.

    Article  PubMed  CAS  Google Scholar 

  9. James, M. O.; Smith, R. L.; Williams, R. T., et al. The conjugation of phenylacetic acid in man, sub-man primates and some non-primate species. Proc. R. Soc. Lond. B. 182:25–35; 1972.

    Article  PubMed  CAS  Google Scholar 

  10. Lippman, S. M.; Parkinson, D. R.; Itri, L. M., et al. 13-cis-retinoic acid and interferonα-2a: effective combination therapy for advanced squamous cell carcinoma of the skin. J. Natl. Cancer Inst. 84:235–241; 1992.

    Article  PubMed  CAS  Google Scholar 

  11. Lo Coco, F.; Avvisati, G.; Diverio, D., et al. Molecular evaluation of response to all-trans-retinoic acid therapy in patients with acute promyelocytic leukemia. Blood 77:1657–1659; 1991.

    PubMed  CAS  Google Scholar 

  12. Mendenhall, C. L.; Rouster, S.; Weesner, R. A new therapy for portal systemic encephalopathy. Am. J. Gastroenterol. 81:540–543; 1986.

    PubMed  CAS  Google Scholar 

  13. Neish, W. J. P. Phenylacetic acid as a potential therapeutic agent for the treatment of human cancer. Experientia. 27:860–861; 1971.

    Article  PubMed  CAS  Google Scholar 

  14. Nichols, K. E.; Chitneni, S. R.; Moore, J. O., et al. Monocytoid differentiation of freshly isolated human myeloid leukemia cells and HL-60 cells induced by the glutamine antagonist acivicin. Blood 74:1728–1737; 1989.

    PubMed  CAS  Google Scholar 

  15. Rosenfeld, H.; Roberts, J. Enhancement of antitumor activity of glutamine antagonists 6-diazo-5-oxo-L-norleucine and acivicin in cell culture by glutaminase-asparaginase. Cancer Res. 41:1324–1328; 1981.

    PubMed  CAS  Google Scholar 

  16. Samid, D.; Shack, S.; Sherman, L. T. Phenylacetate: a novel nontoxic inducer of tumor cell differentiation. Cancer Res. 52:1988–1992; 1992.

    PubMed  CAS  Google Scholar 

  17. Samid, D.; Yeh, T.-J.; Shack, S. Interferon in combination with antitumorogenic phenyl derivatives: potentiation of IFNα activityin-vitro. Br. J. Hematol. 79:81–83; 1991.

    CAS  Google Scholar 

  18. Samid, D.; Shack, S.; Myers, C. E., et al. Phenylacetate, a novel inducer of tumor cell differentiation. AACR 83 Annual Meeting Proceedings; 1992:3122.

  19. Samid, D.; Shack, S.; Myers, C. E. Phenylacetate in suppression of human prostate adenocarcinoma cell growth and invasion. AACR 83 Annual Meeting Proceedings: 1992:3121.

  20. Shechter, Y.; Sakal, E.; Cohen, R., et al. Hydroxypenyl acetate derivatives inhibit protein tyrosine kinase activity and proliferation in NB2 rat lymphoma cells and insulin-induced lipogenesis in rat adipocytes. Mol. Cell. Endocrinol. 80:183–192; 1991.

    Article  PubMed  CAS  Google Scholar 

  21. Simell, O.; Sipila, I.; Rajantie, J., et al. Waste nitrogen excretion via amino acid acylation: benzoate and phenylacetate in lysinuric protein intolerance. Pediatr. Res. 20:1117–1121; 1986.

    Article  PubMed  CAS  Google Scholar 

  22. Smith, M. A.; Parkinson, D. R.; Cheson, B. D., et al. Retinoids in cancer therapy. J. Clin. Oncol. 10:839–864; 1992.

    PubMed  CAS  Google Scholar 

  23. Straus, D. S.; Takemoto, C. D. Amino acid limitation negatively regulates insulin-like growth factor-II mRNA levels and E-domain peptide secretion at a post-transcriptional step in BRL-3A rat liver cells. J. Biol. Chem. 263:18404–18410; 1988.

    PubMed  CAS  Google Scholar 

  24. Thiele, C. J.; Reynolds, C. P.; Israel, M. A. Decreased expression of N-myc precedes retinoic acid-induced morphological differentiation of human neuroblastoma. Nature 313:404–406; 1985.

    Article  PubMed  CAS  Google Scholar 

  25. Warrell, R. P.; Frankel, S. R.; Miller, W. H., et al. Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans-retinoic acid). N. Engl. J. Med. 324:1385–1393; 1991.

    Article  PubMed  Google Scholar 

  26. Weber, G. Biochemical strategy of cancer cells and the design of chemotherapy: G.H.A. Clowes Memorial Lecture. Cancer Res. 43:3466–3492; 1983.

    PubMed  CAS  Google Scholar 

  27. Weinberg, J. B.; Mason, S. N. Relationship of acivicin-induced monocytoid differentiation of human myeloid leukemia cells to acivicininduced modulation of growth factor, cytokine, and protooncogene mRNA expression. Cancer Res. 51:1202–1209; 1991.

    PubMed  CAS  Google Scholar 

  28. Wightman, F.; Lighty, D. L. Identification of phenylacetic acid as a natural auxin in the shoots of higher plants. Physiol. Plant. 55:17–24; 1982.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Pediatrics Division of Pediatric Hematology/Oncology, Cooper Hospital/University Medical Center and UMDNJ-Robert Wood Johnson Medical School at Camden Three Cooper Plaza, Suite 410, 08103, Camden, New Jersey

    Grzegorz K. Górski, Milton H. Donaldson & Lydia E. McMorrow

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  1. Grzegorz K. Górski
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  2. Milton H. Donaldson
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  3. Lydia E. McMorrow
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Górski, G.K., Donaldson, M.H. & McMorrow, L.E. Synergistic inhibition of human rhabdomyosarcoma cells by sodium phenylacetate and tretinoin. In Vitro Cell Dev Biol - Animal 29, 189–191 (1993). https://doi.org/10.1007/BF02634180

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