Zusammenfassung
Um zu prüfen, ob die Reaktion des Dünndarms auf hochfrequente Elektrostimulation von der Nahrungsaufnahme beeinflußt wird, wurden nach einer Serie von Akutversuchen bei 2 Hunden eine Jejunumschlinge und bei weiteren 2 ein Jejunumpouch mit Elektroden und Druckmeßsonden bestückt und am wachen Tier im chronischen Versuch untersucht. 500-μsec-910-Hz-25-mA-Ströme erhöhten den Druck in der Jejunumschlinge um 26±22 mm Hg (n=10) beim nüchternen und um 21±23 mm Hg (n=9) beim gefütterten Tier. Der Pouch war beim gefütterten Tier schwieriger zu stimulieren. Durch Elektrostimulation ist es möglich, am wachen Tier Dünndarmkontraktionen auszulösen, welche nur im Falle des Dünndarmpouches vom Status der Nahrungsaufnahme beeinflußt werden.
Summary
To prove whether food intake influences the reaction of the small intestine to electrostimulation 4 dogs were chronically investigated after a series of acute studies. Stimulation with 500 μsec 910 Hz 25 mA currents raised the intraluminal pressure by 26±33 mm Hg in the jejunal loop in the fasted and by 21±23 mm Hg in the fed animal. Pouches were difficult to stimulate in fed dogs. Intestinal loops and pouches may be contracted by electrostimulation in awake animals. Feeding inhibits the reaction in intestinal reservoirs.
Literatur
Bennett MR: Rebound excitation of the smooth muscle cells of the guinea pig taenia coli after stimulation of intramural inhibitory nerves. J Physiol 1996;185:148.
Brolin RE, Semmlow JL, Koch RA, Reddell MT, Mast BA, Mackenzie JW: Myoelectric assessment of bowel viability. Surgery 1987;102:32.
Campbell G: Nerve mediated excitation of the taenia of the guinea pig caecum. J Physiol 1966;185:148.
Cole OF, Marquis VD: A pharmacological analysis of the responses of the gastrointestinal smooth muscle of the bat to transmural and periarterial nerve stimulation. Br J Pharmacol 1985;84:587.
Collman PI, Grundy D, Scratcherd T: Vagal influences on the jejunal minute rhythm in the anesthetized ferret. J Physiol (Lond) 1983;345:65.
Costall B, Gunning SJ, Naylor RJ, Tattersall FD: Modification of electrical field stimulation-induced contractions in the guinea pig ileum by metoclopramide and ICS 205-930 depends on the integrity of the mucosa. J Pharm Pharmacol 1986;38:811.
Faendriks L, Joenson C, Nylander O: Effects of splanchnic nerve stimulation and of clonidine gastric and duodenal HCO3 secretion in the anesthetized cat. Acta Physiol Scand 1987;130:251.
Gillis RA, Dias Souza J, Hicks KA, Mangel AW, Pagani FD, Hamilton BL, Garvey TQ, Pace DG, Browne RK, Norman WP: Inhibitory control of proximal colonic motility by the sympathetic nervous system. Am J Physiol 1987;253:G531.
Grundfest-Broniatowsky S, Moritz A, Moritz A, Ilyes L, Jacobs G, Kasick J, Olsen E, Nose Y: Voluntary control of an ileal pouch by coordinated electrical stimulation—a pilot study in the dog. Dis Colon Rectum 1988;31:261.
Holman ME, Hughes JR: Inhibition of intestinal smooth muscle. Aust J Biol Med Sci 1965;43:277.
Moritz A, Grundfest-Broniatowsky S, Ilyes L, Jacobs G, Kasick J, Nose Y: Mechanical response to electrical stimulation of intestinal loops and pouches, Proc 2nd Vienna International Workshop on Functional electrostimulation. Vienna, September 21–24, 1986, p 227.
Paton WD: The response of the guinea pig ileum to electrical stimulation by coaxial electrodes. J Phys (Lond) 1955;127:40.
Szurszewsky JH: The migrating electric complex of the canine small intestine. Am J Physiol 1969;217:1757.
Varma JS, Binnie N, Smith AN, Creasey GH, Edmond P: Differential effects of sacral anterior root stimulation on anal sphincter and colorectal motility in spinally injured man. Br J Surg 1986;73:478.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Moritz, A., Grundfest-Broniatowski, S., Ilyes, L. et al. Die Rekation des Dünndarms auf transmurale Elektrostimulation beim nüchternen und gefütterten Tier. Acta Chir Austriaca 22, 205–209 (1990). https://doi.org/10.1007/BF02633760
Issue Date:
DOI: https://doi.org/10.1007/BF02633760