References
Albert, D. M.; Saulienas, A. M.; Cohen, S. M. Verhoett’s query: is vitamin D effective against retinoblastoma? Arch. Ophthalmol. 106:536–540; 1988.
Beckman, M. J.; Horst, R. L.; Reinhardt, T. A., et al. Up-regulation of the intestinal 1,25-dihydroxyvitamin D receptor during hypervitaminosis D: a comparison between vitamin D2 and vitamin D3. Biochem. Biophys. Res. Commun. 29:910–915; 1990.
Bosch, R.; Thijssen, J. H.; Duursma, S. A. Action and metabolism of dihydrotachysteroid. J. Steroid Biochem. 27:829–836; 1987.
Collins, S. J.; Gallo, R. C.; Gallagher, R. E. Continuous growth and differentiation of human myeloid leukemia cells in suspension culture. Nature (Lond.) 270:347–349; 1977.
Hartwell, D.; Hassager, C.; Christiansen, C. Effect of vitamin D2 and vitamin D3 on the serum concentrations of 1,25(OH)2D2, and 1,25(OH)2D3 in normal subjects. Acta. Endocrinol. 115:378–384; 1987.
Hartwell, D.; Christiansen, C. Comparisons between two receptor assays for 1,25-dihydroxyvitamin D. Scand. J. Clin. Lab. Invest. 48:109–114; 1988.
Horst, R. L.; Koszewski, N. J.; Reinhardt, T. A. 1 alpha-hydroxylation of 24-hydroxyvitamin D2 represents a minor physiological pathway for the activation of vitamin D2 in mammals. Biochem. 29:578–582; 1990.
Mangelsdorf, D. J.; Koeffler, H. P.; Donaldson, C. A., et al. 1,25-dihydroxyvitamin D3-induced differentiation in a human promyelocytic leukemia cells line (HL-60): Receptor-mediated maturation to macrophage-like cells. J. Cell Biol. 98:391–398; 1984.
McCarthy, D. M.; San Miguel, J. F.; Freake, H. C., et al. 1,25-dihydroxyvitamin D3 inhibits proliferation of human promyelocytic leukemia (HL-60) cells and induces monocyte-macrophage differentiation in HL-60 and normal human bone marrow cells. Leuk. Res. 7:51–55; 1983.
Reitsma, P. H.; Rothberg, P. G.; Astrin, S. M., et al. Regulation of myc gene expression in HL-60 leukemia cells by a vitamin D metabolite. Nature 306:492–494; 1983.
Schule, R.; Umesono, K.; Mangelsdorf, D. J., et al. Jun-fos and receptors for Vitamins A and D recognize a common response element in the human osteocalcin gene. Cell 61:497–504; 1990.
Yen, A. Control of HL-60 myeloid differentiation: evidence of uncoupled growth and differentiation control, S-phase specificity and two-step regulation. Exp. Cell Res. 156:198–212; 1984.
Yen, A.; Reece, S. L.; Albright, K. L. Control of cell differentiation during proliferation. II. Myeloid differentiation and cell cycle arrest of HL-60 promyelocytes preceded by nuclear structural changes. Leuk. Res. 9:51–71; 1985.
Yen, A.; Brown, D.; Fishbaugh, J. Control of HL-60 monocytic differentiation. Different pathways and uncoupled expression of differentiation markers. Exp. Cell Res. 168:247–254; 1987.
Yen, A.; Forbes, M. E.; deGala, G., et al. Control of HL-60 cell differentiation lineage specificity: a late event occurring after precommitment. Cancer Res. 47:129–134; 1987.
Yen, A.; Forbes, M. E. C-myc down regulation and precommitment in HL-60 cells due to bromodeoxyuridine. Cancer Res. 50:1411–1420; 1990.
Author information
Authors and Affiliations
Additional information
This work supported in part by the NIH (USPHS), Council for Tobacco Research, American Institute for Cancer Research, and the Cornell Consolidated and Cornell Biotechnology Program which is sponsored by the New York State Science and Technology Foundation, a consortium of industries, the US Army Research Office and the National Science Foundation.
Rights and permissions
About this article
Cite this article
Yen, A., Blue, J. & Forbes, M. 1,25-Dihydroxy vitamin D2 induces leukemia cell differentiation. In Vitro Cell Dev Biol - Animal 27, 518–520 (1991). https://doi.org/10.1007/BF02631279
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02631279