Summary
Detailed roengenological examinations of the esophagus were carried out in 110 diabetics and 130 controls. In 50 (45%) diabetic patients functional abnormalities were detected. Wavy esophageal contours, irregular spontaneous contractions and functional diverticula were observable. In diabetes, these changes occurred at an earlier age and more frequently than in controls. Esophageal transit time was markedly prolonged. The clinical symptoms of dysphagia were usually mild or absent. Diabetic dysphagia is one of the manifestations of diabetic visceral neuropathy. It is attributed mainly to the diabetic damage of the vagus nerve.
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Bailey R., Langille D., Sidorov J. J.: Esophageal dysfunction in diabetes mellitus — Gastroenterology56, 1136, 1969.
Binder H. J., Bloom D. L., Stern H., Solitare W., Thayer H., Spiro E., Poindexter E.: The effect of cervical vagotomy on esophageal function in the monkey — Surgery64, 1075, 1968.
Castell D. O.: Changes in lower esophageal sphincter pressure during insulin-induced hypoglycemia — Gastroenterology61, 10, 1971.
Crispin J., Lind J.: Manometric study of the effect of vagotomy on the gastroesophageal sphincter — Canad. J. Surg.10, 299, 1967.
Ellebute E., Kelley M., Schwartz S.: Pressure effects of transabdominal supradiaphragmatic vagotomy on the inferior esophageal sphincter of dogs — Surg. Gynec. Obstet.123, 326, 1966.
Ellenberg M., Cohen B.: Diabetic esophageal neuropathy — Diabetes17, 322, 1968.
Forgács S.: Motility disorders of the digestive tract in diabetes mellitus — IRCS med. Sci. (73-8), 13-12-1.
Forgács S.: Gastrointestinale Komplikationen des Diabetes mellitus — Med. Klin.70, 1424, 1975.
Forgács S.: Die Entleerungstörungen des Magens beim Diabetes mellitus — Fortschr. Geb. Roentgenstr.122, 541, 1975.
Forgács S.: Gallenblasenveränderungen bei Diabetikern — Radiol. Diagn. (Berl.)17, 51, 1976.
Forgács S., Halmost T., Salamon F.: Diabetic diarrhea — Israel J. med. Sci.8, 784, 1972.
Giorgino R., Viola M., Tafaro E.: Incidence of hiatus hernia in diabetic subjects: remarks on pathogenesis — Acta diabet. lat.8, 1129, 1971.
Goyal R. K., Spiro H. M.: Esophageal function in diabetes mellitus — Ann. intern. Med.72, 281, 1970.
Grossman M. I.: How does insulin stimulate the lower esophageal sphincter? — Gastroenterology61, 119, 1971.
Heitmann D., Strösse U., Gottesbüren G., Martini G.: Störungen der Speiseröhrenfunktion bei Diabetikern — Dtsch. med. Wschr.98, 1151, 1973.
Higgs B., Ellis F.: The effect of bilateral supranodosal vagotomy on canine esophageal function — Surgery58, 828, 1965.
Hollis J. B., Castell D. O., Braddom R. L.: Esophageal function in diabetes mellitus and its relation to peripheral neuropathy — Gastroenterology73, 1098, 1977.
Horgan J. H., Doyle J. S.: A comparative study of esophageal motility in diabetics with neuropathy — Chest60, 170, 1971.
Ihász M.: A postvagotomiás dysphagiáról — Orv. Hetil.115, 2535, 1974.
Kantrowitz P. A., Corson J. G., Fleischli D. J., Skinner J.: Measurement of gastroesophageal reflux — Gastroenterology56, 666, 1969.
Langille D., Brown B. S., Sidorov J. J., Baillie R., Hayne O.: The oesophagus in diabetes mellitus. Cinefluorographic and manometric observations — J. Canad. Ass. Radiol.22, 124, 1971.
Mandelstam P., Lieber A.: Esophageal dysfunction in diabetic neuropathy-gastroenteropathy. Clinical and roentgenological manifestations — J. Amer. med. Ass.201, 582, 1967.
Mandelstam _., Siegel C. J., Lieber A., Siegel M.: The swallowing disorder in patients with diabetic neuropathy-gastroenteropathy — Gastroenterology56, 1, 1969.
Postlethwait R. W., Kim S. K., Dillon M. L.: Esophageal complications of vagotomy — Surg. Gynec. Obstet.128, 481, 1969.
Silber W.: Diabetes and oesophageal dysfunction — Brit. med. J.3, 688, 1969.
Stewart I., Hosking B., Preston B., Atkinson A.: Esophageal motor changes in diabetes mellitus — Thorax31, 278, 1976.
Vela A. R., Belart L.: Esophageal motor manifestations in diabetes mellitus — Amer. J. Surg.119, 21, 1970.
Vix V. A.: Esophageal motility in diabetes mellitus — Radiology92, 363, 1969.
Woodward B., Alexander-Williams I., Atkinson M.: Effect of subdiaphragmatic vagotomy on the function of gastro-oesophageal sphincter — Gut7, 713, 1966.
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Forgács, S., Osváth, J., Kéri, Z. et al. Esophageal dysfunction in diabetes mellitus. Acta diabet. lat 16, 227–234 (1979). https://doi.org/10.1007/BF02629116
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DOI: https://doi.org/10.1007/BF02629116