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Malignant transformation of perianal condyloma acuminatum: A case report with review of the literature

  • Published:
Diseases of the Colon & Rectum

Abstract

A case of squamous-cell carcinoma arising in association with perianal condyloma acuminatum was studied by light microscopy. The eight previously reported cases of malignant transformation of perianal and anorectal condylomata acuminatum are reviewed and the salient features described. Light microscopic examination of the case reported here demonstrated several foci of subtle and abrupt transition from condyloma acuminatum to epithelial dysplasia and to carcinomain situ with focal frank invasion. This study further substantiates the existence of malignant transformation of condyloma acuminatum, particularly in perianal skin.

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Authors and Affiliations

  1. Department of Pathology and Oncology, University of Kansas College of Health Sciences and Hospital, Kansas City, Kansas

    Saing H. Lee M.D., Douglas H. McGregor M.D. & Mohamed N. Kuziez M.D.

  2. Laboratory Service, Veterans Administration Medical Center, 4801 Linwood Boulevard, 64128, Kansas City, Missouri

    Saing H. Lee M.D., Douglas H. McGregor M.D. & Mohamed N. Kuziez M.D.

Authors
  1. Saing H. Lee M.D.
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  2. Douglas H. McGregor M.D.
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  3. Mohamed N. Kuziez M.D.
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Lee, S.H., McGregor, D.H. & Kuziez, M.N. Malignant transformation of perianal condyloma acuminatum: A case report with review of the literature. Dis Colon Rectum 24, 462–467 (1981). https://doi.org/10.1007/BF02626784

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  • DOI: https://doi.org/10.1007/BF02626784

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