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On the flexibility of surface structures of tumor cells in vitro

In Vitro volume 20, pages 103–108 (1984)Cite this article

Summary

When HeLa cells are detached from their support by trypsin, trypsin-EDTA, or by mechanical means large zeiotic blebs are formed. After reseeding the cells onto glass these blebs shrink. Those blebs near the support collapse completely to form lobes in the neighborhood of lobopodia. By scanning and transmission electron microscopy we could show the transformation of these zeiotic blebs into true lobopodia. This implies a repair of cell surface structures and components as well as of the subcortical cytoskeleton.

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Affiliations

  1. German Cancer Research Center, Institute of Cell and Tumor Biology, D-6900, Heidelberg, Federal Republic of Germany

    Neidhard Paweletz & Eva-Maria Finze

Authors
  1. Neidhard Paweletz
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  2. Eva-Maria Finze
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Paweletz, N., Finze, EM. On the flexibility of surface structures of tumor cells in vitro. In Vitro 20, 103–108 (1984). https://doi.org/10.1007/BF02626650

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  • DOI: https://doi.org/10.1007/BF02626650

Key words

  • zeiotic blebs
  • lobopodia
  • flexibility
  • cytoskeleton