Metabolic effects of honey (alone or combined with other foods) in type II diabetics

Summary

The metabolic effects of honey — alone or combined with other foods — were investigated in type II diabetics using 2 protocols: A) 33 g honey and 50 g bread (same amounts of carbohydrate) were given on alternate days to 12 patients. Blood levels of glucose, insulin and triglycerides were determined in venous samples before and every 30 min after meal ingestion (for a total of 3h). Areas under glucose curves were equal, although honey — compared to bread — resulted in higher blood sugar concentrations at 30 min (p<0.01) and lower at 90 min (p<0.05). B) Another 19 type II diabetics consumed on separate days 3 different meals: H (30 g honey), HA (30 g honey, 100 g almonds), HB (30 g honey, 125 g cheese, 10 g bread, 10 g butter). HA and HB contained the same amount of fat, but were different in fiber. No significant differences in the areas under glucose curves were observed. However, meal H produced earlier hyperglycemia than HA and HB (30 min: p<0.01). Insulin levels were higher after HB compared to H (p<0.05). Meals HA and HB were followed by higher triglyceride levels than H (p<0.05). It is concluded that: 1) honey and bread produce similar degrees of hyperglycemia in type II diabetics. 2) Fatrich foods added to honey do not alter the total hyperglycemic effect but result in higher triglyceride and insulin serum concentrations.

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References

  1. 1.

    Bantle J. P., Laine D. G., Castle C. W., Thomas C. W., Hoogwerf B. J., Goetz F. C.: Postprandial glucose and insulin response to meals containing different carbohydrates in normal and diabetic subjects — New Engl. J. Med.309, 7, 1983.

    PubMed  CAS  Article  Google Scholar 

  2. 2.

    Bornet T., Haardt M. J., Costaglioia D., Blayo A., Slama G.: Sucrose or honey at breakfast have no additional acute hyperglycaemic effect over an isoglucidic amount of bread in type 2 diabetic patients — Diabetologia28, 213, 1985.

    PubMed  Article  CAS  Google Scholar 

  3. 3.

    Coulston A. M., Hollenbeck C. B., Liu C. C., William R. A., Starich G. H., Mazzaferri E. L., Reaven G. M.: Effect of source of dietary carbohydrate on plasma glucose, insulin and gastric inhibitory polypeptide response to test meals in subjects with non-insulin-dependent diabetes mellitus — Amer. J. clin. Nutr.40, 965, 1984.

    PubMed  CAS  Google Scholar 

  4. 4.

    Crapo P. A., Insel J., Sperling M., Kolterman O. G.: Comparison of serum glucose, insulin, and glucagon responses to different types of complex carbohydrate in non-insulin-dependent diabetic patients — Amer. J. clin. Nutr.34, 184, 1981.

    PubMed  CAS  Google Scholar 

  5. 5.

    Crapo P. A., Kolterman O. G., Olefsky J. M.: Effects of oral fructose in normal, diabetic and impaired glucose tolerance subjects — Diabet Care3, 575, 1980.

    Article  CAS  Google Scholar 

  6. 6.

    Eggstein M., Kreutz F. H.: Eine neue Bestimmung der Neutralfette in Blutserum und Gewebe I. Mitteilung (Prinzip, Durchführung und Besprechung der Methode) — Klin. Wschr.44, 262, 1966.

    PubMed  Article  CAS  Google Scholar 

  7. 7.

    Hales C. N., Randle P.J.: Immunoassay of insulin with insulin-antibody precipitate — Biochem. J.88, 137, 1963.

    PubMed  CAS  Google Scholar 

  8. 8.

    Jenkins D. J. A., Chafari H., Wolever T. M. S., Taylor R. H., Barker H. M., Fielden H., Jenkins A. L., Bowling A. C.: Relationship between the rate of digestion of foods and post-prandial glycaemia — Diabetologia22, 450, 1982.

    PubMed  Article  CAS  Google Scholar 

  9. 9.

    Jenkins D. J. A., Wolever T. M. S., Jenkins A. L., Josse R. G., Wong G. S.: The glycaemic response to carbohydrate foods — Lancetii, 388, 1984.

    Article  Google Scholar 

  10. 10.

    Mann J. I.: Simple sugars and diabetes — Diabet Med.4, 135, 1987.

    PubMed  CAS  Google Scholar 

  11. 11.

    Nuttall F. Q., Mooradian A. D., De Marais R., Parker S.: The glycemic effect of different meals approximately isocaloric and similar in protein, carbohydrate, and fat content as calculated using the ADA exchange lists — Diabet Care6, 432, 1983.

    Article  CAS  Google Scholar 

  12. 12.

    Otto H., Niklas L.: Differences d’action sur la glycémie d’aliments contenant des hydrates de carbone: conséquences pour le traitement diététique du diabete sucré — Med. Hyg. (Genève)38, 3424, 1980.

    Google Scholar 

  13. 13.

    Paul A. A., Southgate D. A. T.: McCance and Widdowson’s The composition of foods. Medical Research Council special report No. 297. Her Majesty’s Stationery Office, London, 1978.

    Google Scholar 

  14. 14.

    Samanta A., Burden A. C., Jones G. R.: Plasma glucose responses to glucose, sucrose and honey in patients with diabetes mellitus: an analysis of glycaemic and peak incremental areas — Diabet Med.2, 371, 1985.

    PubMed  CAS  Article  Google Scholar 

  15. 15.

    Slama G., Klein J. -C., Delage A., Ardila E., Lemaignen H., Papoz L., Tchobroutsky G.: Correlation between the nature and amount of carbohydrate in meal intake and insulin delivery by the artificial pancreas in 24 insulin-dependent diabetics — Diabetes30, 101, 1981.

    PubMed  Article  CAS  Google Scholar 

  16. 16.

    Talbot J. M., Fisher K. D.: The need for special foods and sugar substitutes by individuals with diabetes mellitus — Diabet Care1, 231, 1978.

    Article  CAS  Google Scholar 

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Correspondence to Nicholas L. Katsilambros.

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Katsilambros, N.L., Philippides, P., Touliatou, A. et al. Metabolic effects of honey (alone or combined with other foods) in type II diabetics. Acta diabet. lat 25, 197–203 (1988). https://doi.org/10.1007/BF02624814

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Key-words

  • Blood sugar
  • Honey
  • Insulin, Triglycerides
  • Type II diabetics