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Modifications of pancreatic islet tissue after internal biliary fistula (experimental research)

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Summary

The morphometric study of the endocrine pancreas carried out in normal dogs and in dogs with a total internal biliary fistula (cholecystojejunostomy after closure of the common bile-duct) has shown that, following this operation, obvious and statistically significant changes take place which indicate a considerable increase of the insular mass. This anatomic modification, probably induced by the suppression of bile flow into the duodenum, is the result both of hypertrophy and hyperplasia of the endocrine pancreatic apparatus and seems to go hand in hand with an increase in insulinopoietic activity.

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References

  1. Brolin S., Hellman B.: New Methods for Determination of the Pancreatic Islet Volume — Diabetes12, 62, 1963.

    PubMed  CAS  Google Scholar 

  2. Ermini M., Carboni M.: La funzione pancreatica nella derivazione biliare interna. (Ricerca sperimentale) — Recentia med. (Roma)2, 699, 1963.

    CAS  Google Scholar 

  3. Gomori G.: Observations with Differential Stains on Human Islets of Langerhans — Amer. J. Path.17, 395, 1941.

    Google Scholar 

  4. Gomori G.: Aldehyde-Fuchsin: a New Stain for Elastic Tissue — Amer. J. clin. Path.20, 665, 1950.

    CAS  Google Scholar 

  5. Hellman B.: The Volumetric Distribution of the Pancreatic Islet Tissue in Young and Old Rats — Acta endocr. (Kbh.)31, 91, 1959.

    CAS  Google Scholar 

  6. Kyrle J.: Über die Regenerationsvorgänge im tierischen Pankreas — Arch. mikr. Anat.72, 141, 1908.

    Article  Google Scholar 

  7. Laguesse E.: Sur la numération des îlots endocrines de Langerhans dans le pancréas humain — C. R. Soc. Biol. (Paris)58, 504, 1905.

    Google Scholar 

  8. Lazarus S. S., Kolk B. W.: The Effect of Protracted Glucagon Administration on Blood Glucose and on Pancreatic Morphology — Endocrinology63, 359, 1958.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Istituto Di Patologia Speciale Chirurgica E Propedeutica, Clinica I Dell’Università di Pisa, Italy

    Massimo Ermini, Massimo Seccia & Giuseppe Evangelista

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  1. Massimo Ermini
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  2. Massimo Seccia
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  3. Giuseppe Evangelista
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Ermini, M., Seccia, M. & Evangelista, G. Modifications of pancreatic islet tissue after internal biliary fistula (experimental research). Acta diabet. lat 12, 150–159 (1975). https://doi.org/10.1007/BF02624733

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  • DOI: https://doi.org/10.1007/BF02624733

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