Summary
A review of the therapeutic uses of anorectal suppositories is given. The major local effects of suppositories are production of defecation, topical therapy, and relief of pain. Systemic actions are possible from drugs that can be absorbed through the rectal mucosa.
Similar content being viewed by others
References
Banner, E. A.: Rectal suppositories as substitutes for enemas in the postpartum period. Proc. Staff Meet., Mayo Clin.28: 567, 1953.
Bird, V.: Advances in suppositorial therapy. Med. Illus.9: 113, 1955.
Cacchillo, A. F.: Recent advances in suppository medication. U. S. Armed Forces M. J.7: 1009, 1956.
Cacchillo, A. F. and W. H. Hassler: The influence of suppository bases upon the rectal absorption of acetylsalicylic acid. J. Am. Pharm. A. (Scient. Ed.).43: 683, 1954.
Daly, J. W.: Diuretic effect and local tolerance of a new type of mercurial rectal suppository: A preliminary report. Am. J. M. Sc.228: 440, 1954.
Glass, G. B. J., Harry Barowsky, L. J. Boyd, Marilyn Rich, and Leonard Ebin: Theophylline concentration in blood plasma following rectal administration of aminophylline. Am. J. M. Sc.231: 51, 1956.
Kety, S. S.: A medical regimen for benign rectal disorders. GP.10: 75, 1954.
Peterson, C. F., and A. J. Guida: Suppository bases. I. An evaluation of the rates of release of theophylline. J. Am. Pharm. A. (Scient. Ed.).42: 537, 1953.
Rathbun, J. C.: Rectal suppositories for infants and children. Canad. M. A. J.72: 37, 1955.
Riegelman, Sidney, and W. J. Crowell: The kinetics of rectal absorption III. The absorption of undissociated molecules. J. Am. Pharm. A. (Scient. Ed.).47: 127, 1958.
Weiss, Bernard: Rectal suppository medication versus the oral or parenteral route. Am. J. Gastroenterol.27: 70, 1957.
Author information
Authors and Affiliations
About this article
Cite this article
Jackman, R.J. Anorectal suppositories. Dis Colon Rectum 9, 423–426 (1966). https://doi.org/10.1007/BF02617437
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02617437