Computed tomographic characteristics of the normal thymus gland: Relationship to mediastinal hematoma

Abstract

Computed tomography (CT) is frequently used in the screening process to determine the need for angiography in patients with possible blunt thoracic aortic injury. Misinterpretation of normal mediastinal structures (particularly the thymus in patients under age 40 years) as mediastinal hematoma may result in a significant number of false-positive scans.

During a 20-month period, we reviewed the chest CT examinations of 1247 patients to select two groups of patients: group I, in whom the mediastinum was normal by CT, and group II, in whom the CT identification of a mediastinal hematoma had been proven surgically.

Two major mediastinal CT differences were noted between the groups. The first was a normal cleavage plane between the lateral aspect of the aortic arch and the soft tissue density of the thymus seen in 100% of patients with normal mediastinum (group I) and 0% of patients with known mediastinal hematoma (group II). The second difference relates to the anatomic fact that the thymus is normally present only in the anterior mediastinum. Thus, the presence of a soft tissue density throughout the right paratracheal region of the middle mediastinum, which was seen in 100% of group II (mediastinal hematoma) patients and in 0% of group I (normal) patients, represented blood and not thymus tissue.

These results demonstrate fundamental differences in appearance between thymic tissue, regardless of its state of involution, and a mediastinal hematoma on unenhanced mediastinal CT (UMCT). It is important that these differences be recognized so that thymic tissue is not confused with a mediastinal hematoma resulting in unnecessary thoracic aortography.