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New cell line derived from a human chondrosarcoma

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Summary

The morphological, chromosomal, and biological characteristics of a cell line derived from a human chondrosarcoma have been described. At the time of this report, the cell line has undergone 102 passages and continues to exhibit an epithelioid appearance, a modal number of 69 chromosomes, and has retained malignant properties. This cell line is easily cultivated in vitro or in vivo and may prove useful in human cancer research.

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References

  1. Giraldo, G., E. Beth, Y. Hirshaut, T. Aoki, L. J. Old, E. A. Boyse, and H. C. Chopra. 1971. Human sarcomas in culture. J. Exp. Med. 133: 454–478.

    Article  PubMed  CAS  Google Scholar 

  2. Ioachim, H. L. 1970. Tissue culture of human tumors: its use and prospects. Pathol. Annu. 5: 217–246.

    PubMed  CAS  Google Scholar 

  3. Morton, D. L., W. T. Hall, and R. A. Malmgren. 1969. Human liposarcomas: tissue culture containing foci of transformed cells with viral particles. Science 165: 813–816.

    Article  PubMed  CAS  Google Scholar 

  4. Ponten, J., and E. Saksela. 1967. Two establishedin vitro cell lines from human mesenchymal tumors. Int. J. Cancer 2: 434–447.

    Article  PubMed  CAS  Google Scholar 

  5. Aaronson, S. A., G. J. Todaro, and A. E. Freeman. 1970. Human sarcoma cells in culture. Exp. Cell Res. 61: 1–5.

    Article  PubMed  CAS  Google Scholar 

  6. Stewart, S. E., G. Kasnic, C. Draycott, and T. Ben. 1972. Activation of viruses in human tumors by 5-iododeoxyuridine and dimethyl sulfoxide. Science 175: 198–199.

    Article  PubMed  CAS  Google Scholar 

  7. Stewart, S. E., G. Kasnic, C. Draycott, W. Feller, A. Golden, E. Mitchell, and T. Ben. 1972. Activationin vitro by 5-iododeoxyuridine, of a latent virus resembling c-type virus in a human sarcoma cell line. J. Natl. Cancer Inst. 48: 273–277.

    PubMed  CAS  Google Scholar 

  8. Morton, D. L., R. A. Malmgren, W. T. Hall, and G. I. Schidlovsky. 1969. Immunologic studies with human sarcomas. Surgery 66: 152–161.

    PubMed  CAS  Google Scholar 

  9. Moore, G. E., J. R. Mitchen, and L. K. Woods. 1973. Human cell line RPMI M7021 established from a liposarcoma. In Vitro 9: 135–138.

    PubMed  CAS  Google Scholar 

  10. Pumper, R. W., P. Fagan, and W. G. Taylor. 1971. Trypsin sensitivity of mammalian cells grown in a serum-free medium. In Vitro 6: 266–268.

    PubMed  CAS  Google Scholar 

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Winters, W.D., Neri, A. & Morton, D.L. New cell line derived from a human chondrosarcoma. In Vitro 10, 70–76 (1974). https://doi.org/10.1007/BF02615340

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