Abstract
Cytomegalovirus polyradiculopathy, a late complication of HIV infection, is characterized by lower extremity weakness, urinary retention, and sacral dysesthesias. We describe four patients (mean CD4 T-cell count=25 cells/mm3) who developed this “infectious cauda equina syndrome.” The characteristic cerebrospinal fluid (CSF) findings, notably atypical for a viral infection, included polymorphonuclear leukocytosis (mean white blood cell count=1512 cells/mm3, 72% polymorphonuclear leukocytes), elevated protein level (mean=370 mg/dl), and hypoglycorrhacia (mean=28 mg/dl). Physicians who treat patients with HIV should be familiar with this syndrome because early intervention, prior to microbiologic confirmation, provides the best hope for improving neurologic function.
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Meier, P.A., Stephan, K.T. & Blatt, S.P. Cytomegalovirus polyradiculopathy in HIV-infected patients. J Gen Intern Med 11, 47–49 (1996). https://doi.org/10.1007/BF02603486
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DOI: https://doi.org/10.1007/BF02603486