Skip to main content
Log in

Pseudomonas aeruginosa infection: Activation of B suppressor cells which affect cell cooperation in the induction phase of contact sensitivity to oxazolone in mice

  • Published:
Current Microbiology Aims and scope Submit manuscript

Abstract

Pseudomonas aeruginosa depresses contact sensitivity to oxazolone in mice by activating B suppressor cells within the lymph nodes that drain the site of sensitization. These suppressor cells affect the induction phase of the immune response by blocking the cooperation between “stimulator” macrophages and “initiator” T cells on one hand and “recruited” T cells on the other.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literature Cited

  1. Asherson, G. L., Zembala, M., Mayhew, B. 1977. Analysis of the induction phase of contact sensitivity by footpad transfer of regional lymph node cells. Macrophages and radioresistant T lymphocytes induce immunity. Immunology32:81–88.

    PubMed  CAS  Google Scholar 

  2. Bjornson, A. B., Michael, J. J. 1970. Biological activities of rabbit immunoglobulin M and immunoglobulin G antibodies toPseudomonas aeruginosa Infection and Immunity2:453–461.

    PubMed  CAS  Google Scholar 

  3. Campa, M., Garzelli, C., Falcone, G. 1975. Depression of contact sensitivity and enhancement of antibody response inPseudomonas aeruginosa-infected mice. Infection and Immunity12:1252–1257.

    PubMed  CAS  Google Scholar 

  4. Colizzi, V., Garzelli, C., Campa, M., Falcone, G. 1978. Depression of contact sensitivity by enhancement of suppressor cell activity inPseudomonas aeruginosa-injected mice. Infection and Immunity21:354–359.

    PubMed  CAS  Google Scholar 

  5. Floersheim, G. L., Hopff, W. H., Gasser, M., Bucker, K. 1971. Impairment of cell-mediated immune response byPseudomonas aeruginosa. Clinical and Experimental Immunology9:241–247.

    PubMed  CAS  Google Scholar 

  6. Garzelli, C., Colizzi, V., Campa, M., Bozzi, L., Falcone, G. 1979. Depression of the antibody response inPseudomonas aeruginosa-injected mice. Infection and Immunity24:32–38.

    PubMed  CAS  Google Scholar 

  7. Gill, H. K., Liew, F. Y. 1979. Regulation of delayed-type hypersensitivity. IV. Antigen-specific suppressor cells for delayed-type hypersensitivity induced by lipopolysaccharide and sheep erythrocytes in mice. European Journal of Immunology9:101–106.

    Article  PubMed  CAS  Google Scholar 

  8. Munster, A. M., Leary, A. G. 1977. Cell-mediated immune response toPseudomonas aeruginosa. American Journal of Surgery133:710–712.

    Article  PubMed  CAS  Google Scholar 

  9. Raff, M. C. 1969. Theta isoantigen as marker of thymus-derived lymphocytes in mice. Nature224:378–379.

    Article  PubMed  CAS  Google Scholar 

  10. Reynolds, H. Y. 1974. Pulmonary host defenses in rabbits after immunization withPseudomonas antigens: The interaction of bacteria, antibodies, macrophages, and lymphocytes. Journal of Infectious Diseases130:S134-S142.

    PubMed  Google Scholar 

  11. Stone, H. H., Given, K. S., Martin, J. D., Jr. 1967. Delayed rejection of skin homografts inPseudomonas sepsis. Surgery Gynecology and Obstetrics124:1067–1070.

    CAS  Google Scholar 

  12. Trizio, M. C., Cudkowicz, G. 1974. Separation of T and B lymphocytes by nylon wool columns: Evaluation of efficacy by functional assayin vivo. Journal of Immunology113:1093–1097.

    CAS  Google Scholar 

  13. Woodruff, M. F. A., Nolan, B., Robson, J. S., MacDonald, M. K. 1969. Renal transplantation in man. Lanceti:6–12.

    Article  Google Scholar 

  14. Young, L. S. 1974. Role of antibody in infections due toPseudomonas aeruginosa. Journal of Infectious Diseases130:S111-S118.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Campa, M., Colizzi, V., Garzelli, C. et al. Pseudomonas aeruginosa infection: Activation of B suppressor cells which affect cell cooperation in the induction phase of contact sensitivity to oxazolone in mice. Current Microbiology 4, 173–175 (1980). https://doi.org/10.1007/BF02602824

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02602824

Keywords

Navigation