Zusammenfassung
Die Entwicklung der Hypothalamus-Hypophysen-Gonadenachse ist während der Kindheit ein kontinuierlicher Prozeß, der erst mit der Pubertät endet. Kryptorche Hoden beeinträchtigen ernsthaft die Entwicklung der Geschlechtszellen, welche bedeutungsvoller ist, je höher die Hoden liegen und je höher die Gonadotropininsuffizienz ist. Alle Neugeborenen weisen eine normale Anzahl der Geschlechtszellen auf, was signifikant die Theorie unterstützt, daß der Kryptorchismus eine Krankheit und nicht eine Mißbildung ist. Demzufolge ist es nötig, frühzeitig und angemessen die Behandlung der kryptorchen Knaben vorzunehmen, um beste Fertilitätsaussichten zu gewährleisten.
Summary
The development of hypothalamus pituitary gonadal axis during childhood is a continuous process which ends at puberty. Cryptorchid gonads have severe impaiment of their germ cell development which is more pronounced, the higher the gonads are located and the higher gonadotropin deficiency is. All newborns have a normal number of germ cells which strongly support the theory that cryptorchidism is a disease and not a malformation. As a consequence, adequate and early treatment of cryptorchid boys should be undertaken in order to preserve optimal chances of fertility.
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Hadziselimovic, F. Die Bedeutung der Hypothalamus-Hypophysen-Gonadendysfunktion für die Entstehung und Behandlung des Hodenhochstandes. Acta Chir Austriaca 25, 404–407 (1993). https://doi.org/10.1007/BF02602156
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DOI: https://doi.org/10.1007/BF02602156