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Yeast invertase: Subcellular distribution and possible relationship between the isoenzymes

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Abstract

The intracellular invertase ofSaccharomyces cerevisiae is mainly found in a soluble form (91–95%), while only minor amounts are found bound to the internal (4–8%) and plasma membranes (less than 1%). In the processes of derepression or repression, inhibition of RNA or protein synthesis, or in the presence of 2-deoxy-d-glucose, the levels of the membrane-bound and external activities are modified in a way in which their relation is clear, while the soluble enzyme does not change at all. These results, together with the fact that the membrane-bound and the external enzymes are glycoproteins, suggest a precursor-product relationship between the enzymic forms.

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Authors and Affiliations

  1. Departmento de Microbiología, Instituto de Microbiologia Bioquímica, CSIC, Facultades de Farmacia y Ciencias, Universidad de Salamanca, Salamanca, Spain

    Luis Rodríguez, Teresa Ruiz, Julio R. Villanueva & Rafael Sentandreu

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  1. Luis Rodríguez
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  2. Teresa Ruiz
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  3. Julio R. Villanueva
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  4. Rafael Sentandreu
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Rodríguez, L., Ruiz, T., Villanueva, J.R. et al. Yeast invertase: Subcellular distribution and possible relationship between the isoenzymes. Current Microbiology 1, 41–44 (1978). https://doi.org/10.1007/BF02601706

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