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In vitro quantitative study of fibre optic XeCI laser angioplasty. Influence of lasing medium and adventitial resistance to photoablation

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Abstract

In this paper, we present a comparative study of atheromatous human plaque photoablation at 308 nm in air, saline or blood, with the tip of the laser energy delivering fibre in close contact with the sample. The ablation depth, measured on histological sections, is given as a function of the number of shots at different laser fluences. The photoablation efficiency depends mostly on the pathological state of the artery rather than on the irradiation medium A clear resistance of the adventitia to 308 nm photoablation is demonstrated in all media. This finding may be an important safety factor for XeCl human coronary angioplasty.

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Authors and Affiliations

  1. Laboratoire de Physique des Lasers, Université Paris XIII, Av JB Clément, 93430, Villetaneuse

    E. Delettre & S. Avrillier

  2. Hopital D. Larrey, 1 rue de l'indépendance américaine, 78013, Versailles Cedex

    Y. Rougier

  3. HIA du Val de Grace, 74 Bd de Port Royal, 75005, Paris

    J. P. Ollivier

Authors
  1. E. Delettre
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  2. S. Avrillier
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  3. Y. Rougier
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  4. J. P. Ollivier
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Delettre, E., Avrillier, S., Rougier, Y. et al. In vitro quantitative study of fibre optic XeCI laser angioplasty. Influence of lasing medium and adventitial resistance to photoablation. Laser Med Sci 7, 111–119 (1992). https://doi.org/10.1007/BF02594060

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  • DOI: https://doi.org/10.1007/BF02594060

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