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Lasers in Medical Science

, Volume 3, Issue 1–4, pp 111–117 | Cite as

A new device for inducing deep localized vaporization in liver with the Nd-YAG laser

  • G. Godlewski
  • P. Sambuc
  • J. J. Eledjam
  • S. Rouy
  • C. Pignodel
  • A. Ould-Said
  • J. M. Bourgeois
Article

Abstract

A new device, composed of a hand-piece (250 mm in length, and 5 mm in diameter) connected to a cooling circulation, has been developed for the purpose of inducing focal coagulation deep in the liver, using a high-power Nd-YAG laser. The device, guiding and protecting the optical fibre, withstands a power-setting of 100 W and allows means transmission of 80% during intrahepatic application with an average power density of 10 200 W/cm2. Thirty-six lesions of 12–18 mm in diameter were made in 11 pigs under ultrasound control with laser shorts of 80 W mean power output for 10s duration. Intrahepatic thermocouples showed a high rise in temperature in the core of the lesion, inducing vaporization, while moderate hyperthermia (54.4%C/60s on average), high enough for tumour cell kill, was observed 1 cm from the laser source. Immediately after irradiation ultrasound revealed a central echo-free lesion, well defined on day 3 by a hyperechoic border and invaded from day 20 by internal hyperechoic enhancement. Anatomical examination demonstrated, on day 0, an excavated site of vaporization which was surround, from day 3 on wards, by an increasing ring of connective tissue, and which was covered, from day 30 onwards, by a fibrotic network gaining ground towards the centre of the lesion. Good healing free of complications, was observed after four months' follow-up. The technique is proposed for photocoagulation of deep metastases.

Key words

Nd-YAG laser photocoagulator Deep vaporization Intrahepatic focal lesion Intraoperative ultrasound 

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Copyright information

© Baillière Tindall 1988

Authors and Affiliations

  • G. Godlewski
    • 1
  • P. Sambuc
    • 1
  • J. J. Eledjam
    • 1
  • S. Rouy
    • 2
  • C. Pignodel
    • 2
  • A. Ould-Said
    • 1
  • J. M. Bourgeois
    • 3
  1. 1.Laboratory of Experimental Anatomy, Faculty of MedicineUniversité Montpellier 1NimesFrance
  2. 2.Laboratory of Histopathology, Faculty of MedicineUniversité Montpellier 1NimesFrance
  3. 3.Laboratory of Ultrasound, Faculty of MedicineUniversité Montpellier 1NimesFrance

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