Lasers in Medical Science

, Volume 3, Issue 1–4, pp 41–45 | Cite as

Molecular aspects in tumour photochemotherapy

  • D. Brault


Photochemotherapy is based on the selective retention by tumours of a photosensitizer which can then be inactivated upon local irradiation by visible laser light. The process involves the photosensitized generation of reactive intermediate species, such as singlet oxygen, with deleterious effects on the diseased tissues. Some fundamental aspects relevant to this new method are examined. Emphasis is given to the interactions of photosensitizers with membranes and to directions for the development of more efficient molecules.

Key words

Photochemotherapy Tumours 


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Copyright information

© Baillière Tindall 1988

Authors and Affiliations

  • D. Brault
    • 1
  1. 1.Laboratoire de Biophysique, INSERM U.201, CNRS UA.481Muséum National d'Histoire NaturelleParisFrance

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