Lasers in Medical Science

, Volume 3, Issue 1–4, pp 21–25 | Cite as

Porphyrin-sensitized phototreatment as a conservative therapy in gynaecological oncology

  • A. Gadducci
  • V. Facchini
  • A. Tau
  • L. Colombi
  • P. Fioretti
  • M. F. Vigna
  • I. Cozzani


Three patients having neoplastic lesions of the lower genital tract were treated by photodynamic therapy, using haematoporphyrin IX hydrochloride as sensitizer and a non-coherent red light. Irradiations were performed at 12, 24, 48 and 72 h from dye injection for 15 min at a fluence of 0.6 W/cm2. The successful outcome of the therapy and the prospects for photodynamic therapy in gynaecological oncology are discussed.


Haematoporphyrin Photodynamic therapy Photonecrosis Gynaecological oncology 


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Copyright information

© Baillière Tindall 1988

Authors and Affiliations

  • A. Gadducci
    • 1
  • V. Facchini
    • 1
  • A. Tau
    • 1
  • L. Colombi
    • 1
  • P. Fioretti
    • 1
  • M. F. Vigna
    • 2
  • I. Cozzani
    • 2
  1. 1.Istituto di Clinica Ginecologica ed Ostetrica dell'Università di PisaItaly
  2. 2.Cattedra di Biochimica ApplicataFacoltà di Medicina e Chirurgia dell'Università di Reggio CalabriaItaly

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