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Isotypes of human vaccinal antibodies to the Vi capsular polysaccharide ofSalmonella typhi

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International Journal of Clinical and Laboratory Research

Summary

The immunoglobulin class and IgG subclass distribution of anti-Vi antibodies elicited by vaccination with a single injection of the purified polysaccharide or three injections of the inactivated whole cell typhoid vaccine was examined using an immunoenzymatic assay. The two vaccines induced antibody responses of similar magnitude and the predominant subclass of IgG antibodies was IgG1.

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Authors and Affiliations

  1. Laboratory of Immunology and Immunopathology (CNRS URA 1172, Immunology and Molecular Interactions), Poitiers University Hospital, BP 577, F-86021, Poitiers Cedex, France

    Jean-Christophe Brugier, Anne Barra & Jean-Louis Preud’homme

  2. Institut Mérieux, Lyon, France

    Dominique Schulz

Authors
  1. Jean-Christophe Brugier
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  2. Anne Barra
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  3. Dominique Schulz
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  4. Jean-Louis Preud’homme
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Brugier, JC., Barra, A., Schulz, D. et al. Isotypes of human vaccinal antibodies to the Vi capsular polysaccharide ofSalmonella typhi . Int J Clin Lab Res 23, 38–41 (1993). https://doi.org/10.1007/BF02592279

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